M
Michael P. Vallely
Researcher at University of Sydney
Publications - 129
Citations - 3738
Michael P. Vallely is an academic researcher from University of Sydney. The author has contributed to research in topics: Off-pump coronary artery bypass & Aortic dissection. The author has an hindex of 27, co-authored 129 publications receiving 3077 citations. Previous affiliations of Michael P. Vallely include Macquarie University & The Heart Research Institute.
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Journal ArticleDOI
Haemolysis during sample preparation alters microRNA content of plasma.
Michaela B. Kirschner,Steven Kao,Steven Kao,J. James B. Edelman,Nicola J. Armstrong,Michael P. Vallely,Nico van Zandwijk,Glen Reid +7 more
TL;DR: It is found that levels of miR-16, a commonly used reference gene, showed little variation when measured in plasma samples from healthy volunteers or patients with malignant mesothelioma or coronary artery disease, and increases in plasma miR -16 andMiR-451 are caused by haemolysis.
Journal ArticleDOI
The Impact of Hemolysis on Cell-Free microRNA Biomarkers.
Michaela B. Kirschner,J. James B. Edelman,J. James B. Edelman,Steven Kao,Michael P. Vallely,Michael P. Vallely,Nico van Zandwijk,Glen Reid +7 more
TL;DR: The microRNA content of hemolyzed and non-hemolyzed plasma as well as RBCs was profiled to obtain a profile of microRNAs in the circulation affected or unaffected by hemolysis, highlighting the importance of rigorous quality control of plasma/serum samples used for measurement of circulating micro RNAs.
Journal ArticleDOI
Diagnostic accuracy of transbronchial lung cryobiopsy for interstitial lung disease diagnosis (COLDICE): a prospective, comparative study.
Lauren K. Troy,Lauren K. Troy,Christopher Grainge,Tamera J. Corte,Tamera J. Corte,Jonathan P. Williamson,Jonathan P. Williamson,Michael P. Vallely,Michael P. Vallely,Wendy A Cooper,Wendy A Cooper,Annabelle Mahar,Jeffrey L. Myers,Simon Lai,Ellie Mulyadi,Paul J. Torzillo,Paul J. Torzillo,Martin J. Phillips,Martin J. Phillips,Helen E. Jo,Helen E. Jo,Susanne Webster,Qi T. Lin,Jessica E Rhodes,Matthew Salamonsen,Jeremy P. Wrobel,Jeremy P. Wrobel,Benjamin Harris,Benjamin Harris,Garrick Don,Peter Wu,Benjamin J. Ng,Christopher Oldmeadow,Ganesh Raghu,Edmund M.T. Lau,Edmund M.T. Lau,David T Arnold,Christopher Cao,Amy Cashmore,Shannon Cleary,Tiffany-Jane Evans,Bruce French,Monika Geis,Laura M. Glenn,Michael Hibbert,Alvin J. Ing,Allen James,Graham Meredith,Christopher Merry,Anand Pudipeddi,Tajalli Saghaie,Rajesh Thomas,Claire Thomson,Scott H. Twaddell +53 more
TL;DR: High levels of agreement between TBLC and SLB for both histopathological interpretation and MDD diagnoses were shown, and these data support the clinical utility of TBLC in interstitial lung disease diagnostic algorithms.
Journal ArticleDOI
Restoring expression of miR-16: a novel approach to therapy for malignant pleural mesothelioma
Glen Reid,M.E. Pel,Michaela B. Kirschner,Yuen Yee Cheng,Nancy Mugridge,Jocelyn Weiss,Marissa Williams,Casey M. Wright,J. James B. Edelman,Michael P. Vallely,Brian C. McCaughan,Sonja Klebe,Himanshu Brahmbhatt,Jennifer A. MacDiarmid,N. van Zandwijk +14 more
TL;DR: The miR-15/16 family is downregulated and has tumour suppressor function in MPM, and reinstatement ofMiR-16 expression represents a novel therapeutic approach for MPM.
Journal ArticleDOI
Coronary Artery Bypass Grafting With and Without Manipulation of the Ascending Aorta: A Network Meta-Analysis.
Dong Fang Zhao,J. James B. Edelman,Michael Seco,Paul G. Bannon,Michael K. Wilson,Michael Byrom,Vinod H. Thourani,Andre Lamy,David P. Taggart,John D. Puskas,Michael P. Vallely +10 more
TL;DR: Avoidance of aortic manipulation in anOPCABG may decrease the risk of post-operative stroke, especially in patients with higher stroke risk, and the elimination of cardiopulmonary bypass may reduce the risk of short-term mortality, renal failure, atrial fibrillation, bleeding, and length of intensive care unit stay.