Michele Navarra

TL;DR: Complex plastic changes take place in NPY system during ACD intoxication and subsequent withdrawal in rat hippocampal formation and NAcc, showing that the pharmacological inhibition of CB1 signaling could counteract the neurochemical imbalance associated with ACD, and alcohol withdrawal, likely boosting the setting up of homeostatic functional recovery.

TL;DR: Clinical studies on the therapeutic applications of BEO exclusively focus on the field of aromatherapy, suggesting that its use can be useful for reducing anxiety and stress.

TL;DR: This work formulated BEO liposomes that improved the water solubility of the phytocomponents and increased their anticancer activity in vitro against human SH-SY5Y neuroblastoma cells, and the results warrant further investigation of BEOliposomes for in vivo applications.

TL;DR: Analysis of clinical studies and evaluation of the cranberry efficacy/safety ratio in the prevention of UTIs strongly support the use of cranberry in the prophylaxis of recurrent UTIs in young and middle-aged women, and evidence of its clinical use among other patients remains controversial.

TL;DR: In this study, insight is gained into the mechanism(s) of neurotoxicity elicited by the viral glycoprotein using the human neuroblastoma CHP100 cell line as an experimental model and suggests that the neuronal injury observed in HIV‐1 infection could be due to direct (or indirect) interactions between the viral protein gp120 and chemokine and/or NMDA receptors.