Michelle D. Tibbs

TL;DR: Microstructural damage to critical memory regions, including the hippocampus and medial temporal lobe WM, were associated with post-RT memory decline, representing possible avoidance targets for memory preservation.

TL;DR: In this article, imaging biomarkers of microstructural injury within the corpus callosum (CC) and intrahemispheric white matter tracts (IHWM) subserve critical aspects of attention and processing speed.

TL;DR: Primary brain tumor patients experience language fluency and naming function may be explained by microstructural injury to left-sided perisylvian white matter, representing potential dose-avoidance targets for language preservation.

TL;DR: Among primary brain tumor patients receiving RT, increased depression and anxiety were independently associated with worsened neurocognition, particularly in attention/processing speed.

TL;DR: The data support a model where TCR-induced phosphorylation of Dlg1 Y222 is a key point of control that endows D lg1AB with the ability to coordinate p38 activation and proinflammatory cytokine production, and propose blocking DlG1ABosphorylation as a novel therapeutic target to specifically block proinflammatoryocyte production but not cytotoxicity.