M
Michelle Ploughman
Researcher at Memorial University of Newfoundland
Publications - 96
Citations - 3213
Michelle Ploughman is an academic researcher from Memorial University of Newfoundland. The author has contributed to research in topics: Aerobic exercise & Medicine. The author has an hindex of 23, co-authored 84 publications receiving 2584 citations. Previous affiliations of Michelle Ploughman include St. John's University.
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Journal ArticleDOI
Brain-Derived Neurotrophic Factor Contributes to Recovery of Skilled Reaching After Focal Ischemia in Rats
Michelle Ploughman,Victoria Windle,Crystal L. MacLellan,Nicole White,Jules J. E. Doré,Dale Corbett +5 more
TL;DR: This study is the first to identify a critical role for BDNF in rehabilitation-induced recovery after stroke, and the results suggest that new treatments to enhance BDNF would constitute a promising therapy for promoting recovery of function after stroke.
Journal ArticleDOI
Exercise is brain food: The effects of physical activity on cognitive function
TL;DR: Moderate physical activity is important for youth whose brains are highly plastic and perhaps even more critical for young people with physical disability.
Journal ArticleDOI
Efficacy and safety of non-immersive virtual reality exercising in stroke rehabilitation (EVREST): a randomised, multicentre, single-blind, controlled trial
Gustavo Saposnik,Gustavo Saposnik,Leonardo G. Cohen,Muhammad Mamdani,Sepideth Pooyania,Michelle Ploughman,Donna Cheung,Jennifer Shaw,Judith Hall,Peter Nord,Sean P. Dukelow,Yongchai Nilanont,Felipe de los Rios,Lisandro Olmos,Mindy F. Levin,Robert Teasell,Ashley Cohen,Kevin E. Thorpe,Andreas Laupacis,Mark Bayley +19 more
TL;DR: In patients who had a stroke within the 3 months before enrolment and had mild-to-moderate upper extremity motor impairment, non-immersive virtual reality as an add-on therapy to conventional rehabilitation was not superior to a recreational activity intervention in improving motor function, as measured by WMFT.
Journal ArticleDOI
Endurance exercise regimens induce differential effects on brain-derived neurotrophic factor, synapsin-I and insulin-like growth factor I after focal ischemia.
Michelle Ploughman,Shirley Granter-Button,Garry Chernenko,Budd A. Tucker,Karen M. Mearow,Dale Corbett +5 more
TL;DR: It is suggested that relatively modest exercise intervention can increase proteins involved in synaptic plasticity in areas of the brain that likely subserve motor relearning after stroke.
Journal ArticleDOI
Exercise intensity influences the temporal profile of growth factors involved in neuronal plasticity following focal ischemia.
Michelle Ploughman,Shirley Granter-Button,Garry Chernenko,Zachary Attwood,Budd A. Tucker,Karen M. Mearow,Dale Corbett +6 more
TL;DR: The findings show that although the more intense, motorized running exercise induced a rapid increase in BDNF, the elevation was more short-lived than with voluntary running, and frequent lower intensity exercise episodes has a delayed but sustained effect on BDNF that may support brain remodeling after stroke.