Biventricular performance during volume loading in patients with early septic shock, with emphasis on the right ventricle: A combined hemodynamic and radionuclide study

Effect of Dopamine vs Norepinephrine on Hemodynamics in Septic Shock: Emphasis on Right Ventricular Performance

Medical therapy of pulmonary hypertension. Conventional therapies.

Background Acute right ventricular (RV) hypertension may result in hemodynamic collapse. The associated reduction in left ventricular (LV) end-diastolic volume is thought to result from reduced RV output (secondary to RV ischemia) and adverse direct ventricular interaction. Aortic constriction improves cardiac function in these circumstances; this has been attributed to a reversal of the RV ischemia caused by an increased coronary perfusion pressure. We hypothesized that altered ventricular interaction, potentially via altered septal mechanics, may also contribute to the beneficial effects of aortic constriction. Methods and Results We instrumented nine dogs with ultrasonic dimension crystals to measure RV segment length, septum–to–RV free wall and septum–to–LV free wall diameters, and LV anteroposterior diameter. Catheter-tipped manometers were used to measure LV and RV pressures. Pericardial pressure was measured with flat, liquid-containing balloon transducers. Inflatable cuff constrictors were placed ...

Effects of aortic constriction during experimental acute right ventricular pressure loading : further insights into diastolic and systolic ventricular interaction

Miguel Josa

Papers

Load tolerance of the right ventricle: Effect of increased aortic pressure