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Table Of Integrals Series And Products

Annual Energy Outlook

Precision medicine is a strategy for tailoring clinical decision making to the underlying genetic causes of disease. This Review describes how, despite the straightforward overall principles of precision medicine, adopting it responsibly into clinical practice will require many technical and conceptual hurdles to be overcome. Such challenges include optimized sequencing strategies, clinically focused bioinformatics pipelines and reliable metrics for the disease causality of genetic variants.

Towards precision medicine

Fueled by the availability of more data and computing power, recent breakthroughs in cloud-based machine learning (ML) have transformed every aspect of our lives from face recognition and medical diagnosis to natural language processing. However, classical ML exerts severe demands in terms of energy, memory, and computing resources, limiting their adoption for resource-constrained edge devices. The new breed of intelligent devices and high-stake applications (drones, augmented/virtual reality, autonomous systems, and so on) requires a novel paradigm change calling for distributed, low-latency and reliable ML at the wireless network edge (referred to as edge ML). In edge ML, training data are unevenly distributed over a large number of edge nodes, which have access to a tiny fraction of the data. Moreover, training and inference are carried out collectively over wireless links, where edge devices communicate and exchange their learned models (not their private data). In a first of its kind, this article explores the key building blocks of edge ML, different neural network architectural splits and their inherent tradeoffs, as well as theoretical and technical enablers stemming from a wide range of mathematical disciplines. Finally, several case studies pertaining to various high-stake applications are presented to demonstrate the effectiveness of edge ML in unlocking the full potential of 5G and beyond.

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Wireless Network Intelligence at the Edge

Recently, deep learned enabled end-to-end communication systems have been developed to merge all physical layer blocks in the traditional communication systems, which make joint transceiver optimization possible Powered by deep learning, natural language processing has achieved great success in analyzing and understanding a large amount of language texts Inspired by research results in both areas, we aim to provide a new view on communication systems from the semantic level Particularly, we propose a deep learning based semantic communication system, named DeepSC, for text transmission Based on the Transformer, the DeepSC aims at maximizing the system capacity and minimizing the semantic errors by recovering the meaning of sentences, rather than bit- or symbol-errors in traditional communications Moreover, transfer learning is used to ensure the DeepSC applicable to different communication environments and to accelerate the model training process To justify the performance of semantic communications accurately, we also initialize a new metric, named sentence similarity Compared with the traditional communication system without considering semantic information exchange, the proposed DeepSC is more robust to channel variation and is able to achieve better performance, especially in the low signal-to-noise (SNR) regime, as demonstrated by the extensive simulation results

Deep Learning Enabled Semantic Communication Systems

We consider the problem of joint source and channel coding of structured data such as natural language over a noisy channel. The typical approach to this problem in both theory and practice involves performing source coding to first compress the text and then channel coding to add robustness for the transmission across the channel. This approach is optimal in terms of minimizing end-to-end distortion with arbitrarily large block lengths of both the source and channel codes when transmission is over discrete memoryless channels. However, the optimality of this approach is no longer ensured for documents of finite length and limitations on the length of the encoding. We will show in this scenario that we can achieve lower word error rates by developing a deep learning based encoder and decoder. While the approach of separate source and channel coding would minimize bit error rates, our approach preserves semantic information of sentences by first embedding sentences in a semantic space where sentences closer in meaning are located closer together, and then performing joint source and channel coding on these em-beddings.

Deep Learning for Joint Source-Channel Coding of Text

We analyze a class of generalized two-ray (GTR) fading channels that consist of two line-of-sight (LOS) components with random phase plus a diffuse component. We derive a closed-form expression for the moment-generating function of the signal-to-noise ratio (SNR) for this model, which greatly simplifies its analysis. This expression arises from the observation that the GTR fading model can be expressed in terms of a conditional underlying Rician distribution. We illustrate the approach to derive simple expressions for statistics and performance metrics of interest, such as the amount of fading, the level crossing rate, the symbol error rate, and the ergodic capacity in GTR fading channels. We also show that the effect of considering a more general distribution for the phase difference between the LOS components has an impact on the average SNR.

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MGF Approach to the Analysis of Generalized Two-Ray Fading Models

We consider the problem of joint source and channel coding of structured data such as natural language over a noisy channel. The typical approach to this problem in both theory and practice involves performing source coding to first compress the text and then channel coding to add robustness for the transmission across the channel. This approach is optimal in terms of minimizing end-to-end distortion with arbitrarily large block lengths of both the source and channel codes when transmission is over discrete memoryless channels. However, the optimality of this approach is no longer ensured for documents of finite length and limitations on the length of the encoding. We will show in this scenario that we can achieve lower word error rates by developing a deep learning based encoder and decoder. While the approach of separate source and channel coding would minimize bit error rates, our approach preserves semantic information of sentences by first embedding sentences in a semantic space where sentences closer in meaning are located closer together, and then performing joint source and channel coding on these embeddings.

MOTIVATION Recent advancements in sequencing technology have led to a drastic reduction in the cost of sequencing a genome. This has generated an unprecedented amount of genomic data that must be stored, processed and transmitted. To facilitate this effort, we propose a new lossy compressor for the quality values presented in genomic data files (e.g. FASTQ and SAM files), which comprise roughly half of the storage space (in the uncompressed domain). Lossy compression allows for compression of data beyond its lossless limit. RESULTS The proposed algorithm QVZ exhibits better rate-distortion performance than the previously proposed algorithms, for several distortion metrics and for the lossless case. Moreover, it allows the user to define any quasi-convex distortion function to be minimized, a feature not supported by the previous algorithms. Finally, we show that QVZ-compressed data exhibit better performance in the genotyping than data compressed with previously proposed algorithms, in the sense that for a similar rate, a genotyping closer to that achieved with the original quality values is obtained. AVAILABILITY AND IMPLEMENTATION QVZ is written in C and can be downloaded from https://github.com/mikelhernaez/qvz. CONTACT mhernaez@stanford.edu or gmalysa@stanford.edu or iochoa@stanford.edu SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.

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QVZ: lossy compression of quality values

We consider the problem of spoken language understanding (SLU) of extracting natural language intents and associated slot arguments or named entities from speech that is primarily directed at voice assistants. Such a system subsumes both automatic speech recognition (ASR) as well as natural language understanding (NLU). An end-to-end joint SLU model can be built to a required specification opening up the opportunity to deploy on hardware constrained scenarios like devices enabling voice assistants to work offline, in a privacy preserving manner, whilst also reducing server costs. We first present models that extract utterance intent directly from speech without intermediate text output. We then present a compositional model, which generates the transcript using the Listen Attend Spell ASR system and then extracts interpretation using a neural NLU model. Finally, we contrast these methods to a jointly trained end-to-end joint SLU model, consisting of ASR and NLU subsystems which are connected by a neural network based interface instead of text, that produces transcripts as well as NLU interpretation. We show that the jointly trained model shows improvements to ASR incorporating semantic information from NLU and also improves NLU by exposing it to ASR confusion encoded in the hidden layer.

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Milind Rao

Papers

Deep Learning for Joint Source-Channel Coding of Text

MGF Approach to the Analysis of Generalized Two-Ray Fading Models

Deep Learning for Joint Source-Channel Coding of Text

QVZ: lossy compression of quality values

Speech to Semantics: Improve ASR and NLU Jointly via All-Neural Interfaces.