M
Min Chen
Researcher at Nanjing Agricultural University
Publications - 25
Citations - 317
Min Chen is an academic researcher from Nanjing Agricultural University. The author has contributed to research in topics: Moiety & Pyrazole. The author has an hindex of 9, co-authored 23 publications receiving 159 citations.
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Journal ArticleDOI
Expedient Discovery for Novel Antifungal Leads Targeting Succinate Dehydrogenase: Pyrazole-4-formylhydrazide Derivatives Bearing a Diphenyl Ether Fragment.
Xiaobin Wang,Xiaobin Wang,An Wang,Ling-Ling Qiu,Min Chen,Aimin Lu,Guo-Hua Li,Chunlong Yang,Wei Xue +8 more
TL;DR: The present work provided a non-negligible complement for the structural optimization of antifungal leads targeting SDH and indicated that the skeleton structure of title compounds should be optimized as an N'-(4-phenoxyphenyl)-1H-pyrazole-4-carbohydrazide scaffold.
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Novel Pyrazole-4-acetohydrazide Derivatives Potentially Targeting Fungal Succinate Dehydrogenase: Design, Synthesis, Three-Dimensional Quantitative Structure-Activity Relationship, and Molecular Docking.
Xiaobin Wang,Xiaobin Wang,Mengqi Wang,Ling Han,Fei Jin,Jian Jiao,Min Chen,Chunlong Yang,Wei Xue +8 more
TL;DR: A series of pyrazole-4-acetohydrazide derivatives potentially targeting fungal SDH were constructed and evaluated for their antifungal effects against Rhizoctonia solani, Fusarium graminearum, and Botrytis cinerea as mentioned in this paper.
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Synthesis, Characterization, and Antifungal Activity of Novel Benzo[4,5]imidazo[1,2-d][1,2,4]triazine Derivatives.
TL;DR: The bioassay results demonstrated that most of the title compounds exhibited obvious fungicidal activities at 50 μg/mL, indicating that benzo[4,5]imidazo[1,2-d], 1,2,4]triazine derivatives could be considered as a new leading structure in searching for novel agricultural fungicides.
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Novel 1,3,5-thiadiazine-2-thione derivatives containing a hydrazide moiety: Design, synthesis and bioactive evaluation against phytopathogenic fungi in vitro and in vivo
TL;DR: In vitro antifungal bioassays indicated that most of title compounds displayed good selectivity and specificity aganist Rs relative to Fg, Bc and Cc, and provide a significant reference for the further structural optimization of 1,3,5-thiadiazine-2-thione derivatives bearing a hydrazide moiety as potential fungicides.
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Design and synthesis of novel 2-(6-thioxo-1,3,5-thiadiazinan-3-yl)-N'-phenylacethydrazide derivatives as potential fungicides.
TL;DR: A series of novel 2-(6-thioxo-1,3,5-thiadiazinan-3-yl)-N′-phenylacethydrazide derivatives were designed, synthesized and evaluated for their antifungal activities against Fusarium graminearum, Rhizoctonia solani, Botrytis cinerea and Colletotrichum capsici.