M
Miriam Galvonas Jasiulionis
Researcher at Federal University of São Paulo
Publications - 68
Citations - 1664
Miriam Galvonas Jasiulionis is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Melanoma & Epigenetics. The author has an hindex of 22, co-authored 60 publications receiving 1329 citations. Previous affiliations of Miriam Galvonas Jasiulionis include Ludwig Institute for Cancer Research.
Papers
More filters
Journal ArticleDOI
The Role of SIRT1 on DNA Damage Response and Epigenetic Alterations in Cancer
TL;DR: The recent findings on the interplay among SIRT1, oxidative stress, and DNA repair machinery and its impact on normal and cancer cells are discussed.
Journal ArticleDOI
Oxidative Stress Modulates DNA Methylation during Melanocyte Anchorage Blockade Associated with Malignant Transformation
Ana Cristina Espindola Campos,Fernanda Molognoni,Fabiana H. M. Melo,Luciano Galdieri,Célia Regina Whitaker Carneiro,Vânia D'Almeida,Mariangela Correa,Miriam Galvonas Jasiulionis +7 more
TL;DR: In this article, increased intracellular oxidative species and nitric oxide levels, as well as alterations in the DNA methylation, were observed after melan-a detachment, which were also associated with a decrease in the Hcy element in the methionine (universal methyl donor) cycle.
Journal ArticleDOI
Timp1 interacts with beta-1 integrin and CD63 along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway independently of Akt phosphorylation.
Mariana Toricelli,Fabiana H. M. Melo,Giovani B. Peres,Débora Castanheira Pereira da Silva,Miriam Galvonas Jasiulionis +4 more
TL;DR: The results show that Timp1 is assembled in a supramolecular complex containing CD63 and β1-integrins along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway, independently of Akt phosphorylation.
Journal ArticleDOI
Enhanced OXPHOS, glutaminolysis and β-oxidation constitute the metastatic phenotype of melanoma cells.
Mariana Figueiredo Rodrigues,Emilie Obre,Fabiana H. M. Melo,Gilson C. Santos,Antonio Galina,Miriam Galvonas Jasiulionis,Rodrigue Rossignol,Franklin David Rumjanek,Nivea Dias Amoedo +8 more
TL;DR: The results indicate that progression to metastasis requires mitochondrial function, and 4C11+ cells could be grouped as a subpopulation with a profile that was quite distinct from the other cells investigated in the present study.
Journal ArticleDOI
Melanocyte transformation associated with substrate adhesion impediment.
Sueli Mieko Oba-Shinjo,Mariangela Correa,Tatiana Iervolino Ricca,Fernanda Molognoni,Maria Aparecida da Silva Pinhal,Izabel A Neves,Sueli K.N. Marie,Lucia O. Sampaio,Helena B. Nader,Roger Chammas,Miriam Galvonas Jasiulionis +10 more
TL;DR: This model corroborates the role of adhesion state as a promoting agent in transformation process and demonstrates that cell adhesion disturbances may act as carcinogenic stimuli, at least for a nontumorigenic immortalized melanocyte lineage.