Mislav Jelić

TL;DR: One year after treatment, characterized chondrocyte implantation was associated with a tissue regenerate that was superior to that after microfracture, and the superior structural outcome may result in improved long-term clinical benefit with characterized chontological implantation.

TL;DR: In this article, the effect of recombinant human osteogenic protein-1 (OP-1) for the treatment of acute renal failure after 60 min bilateral renal artery occlusion in rats was evaluated.

TL;DR: Despite the growing interest in this biological approach for cartilage regeneration, knowledge on this topic is still preliminary, as shown by the prevalence of preclinical studies and the presence of low-quality clinical studies.

TL;DR: Exercise is an effective conservative approach, even if long-term effectiveness and optimal dose and administration modalities still need to be clarified, and physical therapies are emerging as viable treatment options, and novel biological approaches are under study.

TL;DR: Cartilage repair has become a focus of increased interest due to its potential to provide pain relief and alter the progression of degenerative disease, with the hope of delaying or obviating the need for joint replacement.