Mohamed I. Hegab

TL;DR: The antiviral evaluation of some selected new products showed that they have promising antiviral activity against hepatitis-A virus (HAV) and herpes simplex virus type-1 (HSV-1).

TL;DR: In this paper, a series of 2,6-disubstituted pyridine ester derivatives and corresponding amides were prepared, and the pharmacological screening showed that many of these obtained compounds have good analgesic, anticonvulsant, and antiparkinsonian activities comparable to Voltarene®, Carbamazepine®, and Benzotropene® as reference drugs.

TL;DR: Preparation of some novel substituted pyrazole and pyrazolo[3,4-d]pyrimidine derivatives revealed promising antiviral activity against herpes simplex virus type-1 in comparison to Acyclovir as a control.

TL;DR: Some chromeno[4,3‐b]quinolines 4a–i were obtained from β‐chloro carboxyaldehydes 3a–c with different aniline derivatives namely, anilines, 4‐fluoroaniline, and 2‐aminophenol and showed significant anti‐inflammatory and ulcerogenic score activities compared to that of indomethacin.

TL;DR: In this article, some new indeno[1′,2′ :4,5]thieno[3,2-e]tetrazolo[1,5-c]pyrimidines and their isomeric [1,2,4]triazolo[4,3]-pyrimidine were prepared from the reaction of 2-aminoindeno[2,1-b]thiophene-3 carbonitrile with different reagents.