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Mohamed R. Shaaban

Researcher at Cairo University

Publications -  94
Citations -  1505

Mohamed R. Shaaban is an academic researcher from Cairo University. The author has contributed to research in topics: Benzimidazole & Moiety. The author has an hindex of 19, co-authored 92 publications receiving 1180 citations. Previous affiliations of Mohamed R. Shaaban include Umm al-Qura University & Tokyo Institute of Technology.

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Construction of Fused Heterocycles by Metal-mediated [2+2?+?2] Cyclotrimerization of Alkynes And/or Nitriles

TL;DR: The main strategies for the synthesis of fused heterocycles by metal-mediated cyclotrimerization of alkynes and/or nitriles as well as their specific syntheses are reviewed in this article.
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Recent advances in the therapeutic applications of pyrazolines

TL;DR: The present review sheds light on the recent therapeutic patent literature describing the applications of pyrazolines and their derivatives on selected activities, including antimicrobial effects, anti-inflammatory, analgesic, antidepressant and anticancer.
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Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety.

TL;DR: The analgesic and anti-inflammatory activities of the newly synthesized compound were investigated in vivo and the analgesic/anti-inflammatory activity of pyrazolo[1,5-a]pyrimidine derivatives was found to be much higher than triazolo[4-bromophenyl)-6-(phenylsulfonyl)-5-(4-methylphenyl)pyrazolo [1, 5-a].
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Single step synthesis of new fused pyrimidine derivatives and their evaluation as potent Aurora-A kinase inhibitors.

TL;DR: Molecular modeling study was carried out in order to rationalize the in vitro anti-tumor results and 2,7-Diphenyl-6-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine and its p-methoxy analogue 4c were found to be equipotent to Doxorubicin as a reference drug.
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Microbiological, histological, and biochemical evidence for the adverse effects of food azo dyes on rats.

TL;DR: The results of this study provide a reliable basis for not only a better understanding of the histological and biochemical effects of food additives, but also for early diagnostics.