M
Monica Beatriz Frungieri
Researcher at Instituto de Biología y Medicina Experimental
Publications - 52
Citations - 2043
Monica Beatriz Frungieri is an academic researcher from Instituto de Biología y Medicina Experimental. The author has contributed to research in topics: Hamster & Receptor. The author has an hindex of 23, co-authored 51 publications receiving 1760 citations. Previous affiliations of Monica Beatriz Frungieri include University of Buenos Aires & Technische Universität München.
Papers
More filters
Journal ArticleDOI
Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARγ: Possible relevance to human fibrotic disorders
TL;DR: It is found that recombinant tryptase, human mast-cell (HMC-1) supernatant, and the PAR2-activating peptide SLIGKV exert fibroproliferative actions in human fibroblasts.
Journal ArticleDOI
Number, distribution pattern, and identification of macrophages in the testes of infertile men.
Monica Beatriz Frungieri,Monica Beatriz Frungieri,Ricardo S. Calandra,Livia Lustig,Viktor Meineke,Frank M. Köhn,Hermann Josef Vogt,Artur Mayerhofer +7 more
TL;DR: Increased numbers of CD68-positive macrophages directly or indirectly are involved in the regulation of steroidogenesis, Sertoli cell activity, germ cell survival, and, in consequence, in the pathogenesis or maintenance of infertility states in the human testes.
Journal ArticleDOI
Human testicular mast cells contain tryptase: increased mast cell number and altered distribution in the testes of infertile men.
Viktor Meineke,Monica Beatriz Frungieri,Berthold Jessberger,Hermann-Josef Vogt,Artur Mayerhofer +4 more
TL;DR: The results suggest that mast cell products, including the potent fibroblast growth factor tryptase, are involved in the thickening of the tubular wall and other changes in infertile testes.
Journal ArticleDOI
Direct effect of melatonin on Syrian hamster testes: melatonin subtype 1a receptors, inhibition of androgen production, and interaction with the local corticotropin-releasing hormone system
Monica Beatriz Frungieri,Artur Mayerhofer,Karina Zitta,Omar Pedro Pignataro,Ricardo Saul Calandra,Ricardo Saul Calandra,Silvia I. Gonzalez-Calvar,Silvia I. Gonzalez-Calvar +7 more
TL;DR: It is indicated that melatonin may act as a local inhibitor of human chorionic gonadotropin-stimulated cAMP and androgen production through mel1a receptors, down-regulation of steroidogenic acute regulatory protein, and key steroidogenic enzymes expression and its interaction with the local CRH system.
Journal ArticleDOI
Exploring Human Testicular Peritubular Cells: Identification of Secretory Products and Regulation by Tumor Necrosis Factor-α
Christoph Schell,Martin Albrecht,Christine Mayer,J. Ullrich Schwarzer,Monica Beatriz Frungieri,Artur Mayerhofer +5 more
TL;DR: In conclusion, these results provide novel insights into the nature of human peritubular cells, which are able to secrete potent signaling molecules and are regulated by TNF-alpha.