M
Moriz Mayer
Researcher at University of Hamburg
Publications - 5
Citations - 2921
Moriz Mayer is an academic researcher from University of Hamburg. The author has contributed to research in topics: Binding site & Ligand (biochemistry). The author has an hindex of 5, co-authored 5 publications receiving 2735 citations.
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Journal ArticleDOI
Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy
Moriz Mayer,Bernd Meyer +1 more
TL;DR: Fast identification of binding activity directly from mixtures of potential ligands is possible with the NMR method described, which is based on saturation transfer to molecules in direct contact to a protein.
Journal ArticleDOI
Group Epitope Mapping by Saturation Transfer Difference NMR To Identify Segments of a Ligand in Direct Contact with a Protein Receptor
Moriz Mayer,Bernd Meyer +1 more
TL;DR: Analysis of STD NMR experiments performed under competitive conditions proved that the two saccharides studied bind at the same receptor site, thereby ruling out unspecific binding.
Journal ArticleDOI
Detecting binding affinity to immobilized receptor proteins in compound libraries by hr-mas std nmr
Journal ArticleDOI
Charakterisierung von Ligandenbindung durch Sättigungstransfer‐Differenz‐NMR‐Spektroskopie
Moriz Mayer,Bernd Meyer +1 more
TL;DR: In this article, a schnelle bestimmung von Bindungsaktivitat direkt aus Mischungen potentieller Liganden is discussed.
Journal ArticleDOI
Mapping the active site of angiotensin-converting enzyme by transferred NOE spectroscopy.
Moriz Mayer,Bernd Meyer +1 more
TL;DR: Of the five fa derivatives, it is found that fa-Phe, fa-Trp, and fa-Gly-Leu-NH(2) bind more strongly to ACE than the other two, and a rapid screening of binding specificity from mixtures is possible by using a large excess of ligand in transferred NOE studies, even when relatively small amounts of protein are present.