M
Motohiro Hirose
Researcher at National Institute of Advanced Industrial Science and Technology
Publications - 66
Citations - 3688
Motohiro Hirose is an academic researcher from National Institute of Advanced Industrial Science and Technology. The author has contributed to research in topics: Mesenchymal stem cell & Bone marrow. The author has an hindex of 30, co-authored 63 publications receiving 3521 citations. Previous affiliations of Motohiro Hirose include Osaka University & Waseda University.
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Journal ArticleDOI
Therapeutic effect of transplanting HGF-treated bone marrow mesenchymal cells into CCl4-injured rats
Suguru Oyagi,Motohiro Hirose,Midori Kojima,Makiko Okuyama,Masaya Kawase,Toshikazu Nakamura,Hajime Ohgushi,Kiyohito Yagi +7 more
TL;DR: The transplantation of BMMCs cultured with HGF effectively treats liver injury in rats and is a promising technique for autologous transplantation in humans with liver injury.
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Novel approach for achieving double-layered cell sheets co-culture: overlaying endothelial cell sheets onto monolayer hepatocytes utilizing temperature-responsive culture dishes.
Masami Harimoto,Masayuki Yamato,Motohiro Hirose,Chie Takahashi,Yuki Isoi,Akihiko Kikuchi,Teruo Okano +6 more
TL;DR: The layered co-culture of hepatocytes and the HAEC sheets, which allows for the expression of differentiated functions of hepatocyte continuously, such as liver lobule, offers a major advancement in liver tissue engineering.
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Creation of designed shape cell sheets that are noninvasively harvested and moved onto another surface.
TL;DR: This novel technique is the only way to create, harvest, and transfer designed shape cell sheets and would have promising applications in tissue engineering.
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Comparison of osteogenic ability of rat mesenchymal stem cells from bone marrow, periosteum, and adipose tissue.
TL;DR: Micro-computed tomographic and histological analyses demonstrated that new bone formation was detected in the composites using BMSCs and PMSCs, although it was hard to detect in other composites, which indicates that B MSCs andPMSCs could be ideal candidates for utilization in practical bone tissue regeneration.
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Cultured autologous human cells for hard tissue regeneration: preparation and characterization of mesenchymal stem cells from bone marrow.
TL;DR: Cell surface antigen analyses using various types of CD antibodies demonstrated that adherent fibroblastic cells derived from fresh human bone marrow are mesenchymal types and the cells showed extensive capability for proliferation and/or differentiation.