Masayuki Yamato

TL;DR: Sutureless transplantation of carrier-free cell sheets composed of autologous oral mucosal epithelial cells may be used to reconstruct corneal surfaces and can restore vision in patients with bilateral severe disorders of the ocular surface.

TL;DR: These results demonstrate that electrically communicative pulsatile 3-D cardiac constructs were achieved both in vitro and in vivo by layering cardiomyocyte sheets.

TL;DR: Novel tissue engineering methodology layering cell sheets to construct 3-D functional tissues without any artificial scaffolds is proposed and should have enormous potential for fabricating clinically applicable myocardial tissues and should promote tissue engineering research fields.

TL;DR: Cell sheet engineering allows for tissue regeneration by either direct transplantation of cell sheets to host tissues or the creation of three-dimensional structures via the layering of individual cell sheets.

TL;DR: A novel cell-sheet manipulation technology using temperature-responsive culture surfaces to generate functional, cultivated corneal epithelial cell sheet grafts that retain stem cells from limbal stem cells expanded ex vivo, and indicates highly promising clinical capabilities for this bioengineered corneAL epithelial sheet.