M
Motojiro Yoshihara
Researcher at National Institute of Information and Communications Technology
Publications - 12
Citations - 1504
Motojiro Yoshihara is an academic researcher from National Institute of Information and Communications Technology. The author has contributed to research in topics: Synaptotagmin 1 & Vesicle fusion. The author has an hindex of 10, co-authored 12 publications receiving 1414 citations. Previous affiliations of Motojiro Yoshihara include Picower Institute for Learning and Memory & Massachusetts Institute of Technology.
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Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.
TL;DR: These findings indicate that nonnuclear events induced by cytoplasmic huntingtin aggregation play a central role in the progressive neurodegeneration observed in Huntington's disease.
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GETDB, a database compiling expression patterns and molecular locations of a collection of gal4 enhancer traps
Shigeo Hayashi,Kei Ito,Yukiko Sado,Misako Taniguchi,Ai Akimoto,Hiroko Takeuchi,Toshiro Aigaki,Fumio Matsuzaki,Hideki Nakagoshi,Teiichi Tanimura,Ryu Ueda,Ryu Ueda,Ryu Ueda,Tadashi Uemura,Motojiro Yoshihara,Satoshi Goto,Satoshi Goto,Satoshi Goto +17 more
TL;DR: This book aims to provide a chronology of key events and researchers' activities in the development of homosexuality, bisexuality, and related disorders over a period of 50 years.
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Synaptotagmin I Functions as a Calcium Sensor to Synchronize Neurotransmitter Release
TL;DR: The data suggest the Ca(2+) cooperativity of neurotransmitter release is likely mediated through synaptotagmin-SNARE interactions, while phospholipid binding and oligomerization trigger rapid fusion with increased release probability.
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Retrograde Signaling by Syt 4 Induces Presynaptic Release and Synapse-Specific Growth
TL;DR: It is demonstrated that postsynaptic calcium 2+ ion (Ca2+) influx through glutamate receptors and subsequent post synapse vesicle fusion trigger a robust induction of presynaptic miniature release after high-frequency stimulation at Drosophila neuromuscular junctions.
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Presynaptic N-type Calcium Channels Regulate Synaptic Growth
TL;DR: It is reported that presynaptic N-type calcium channels not only control neurotransmitter release but also regulate synaptic growth at Drosophila neuromuscular junctions, and linking presynptic voltage-gated calcium entry to downstream calcium-sensitive synaptic growth regulators provides an efficient activity-dependent mechanism for modifying synaptic strength.