M
Mubashir Pervez
Researcher at Washington University in St. Louis
Publications - 2
Citations - 272
Mubashir Pervez is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Bacteremia & Drug resistance. The author has an hindex of 2, co-authored 2 publications receiving 248 citations.
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Journal ArticleDOI
Empiric Combination Antibiotic Therapy Is Associated with Improved Outcome against Sepsis Due to Gram-Negative Bacteria: a Retrospective Analysis
Scott T. Micek,Emily C. Welch,Junaid Khan,Mubashir Pervez,Joshua A. Doherty,Richard M. Reichley,Marin H. Kollef +6 more
TL;DR: Combined empirical antimicrobial therapy directed against Gram-negative bacteria was associated with greater initial appropriate therapy compared to monotherapy in patients with severe sepsis and septic shock, and experience suggests that aminoglycosides offer broader coverage than fluoroquinolones as combination agents for patients with this serious infection.
Journal ArticleDOI
Resistance to empiric antimicrobial treatment predicts outcome in severe sepsis associated with Gram-negative bacteremia.
Scott T. Micek,Emily C. Welch,Junaid Khan,Mubashir Pervez,Joshua A. Doherty,Richard M. Reichley,Joan Hoppe-Bauer,W. Michael Dunne,Marin H. Kollef +8 more
TL;DR: In severe sepsis attributed to Gram-negative bacteremia, initial treatment with an antibiotic regimen to which the causative pathogen is resistant was associated with increased hospital mortality, suggesting that rapid determination of bacterial susceptibility could influence treatment choices in patients with severe sePSis potentially improving their clinical outcomes.