M
Muhammad Ikram
Researcher at UPRRP College of Natural Sciences
Publications - 27
Citations - 1840
Muhammad Ikram is an academic researcher from UPRRP College of Natural Sciences. The author has contributed to research in topics: Neuroinflammation & Neuroprotection. The author has an hindex of 15, co-authored 27 publications receiving 879 citations. Previous affiliations of Muhammad Ikram include Gyeongsang National University.
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Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer's Disease.
Tahir Ali,Tae Hyun Kim,Shafiq Ur Rehman,Muhammad Sohail Khan,Faiz Ul Amin,Mehtab Khan,Muhammad Ikram,Myeong Ok Kim +7 more
TL;DR: It is suggested that consumption and supplementation of natural-derived anti-oxidant neuroprotective agent such as anthocyanins may be beneficial and suggest new dietary-supplement strategies for intervention in and prevention of progressive neurodegenerative diseases, such as AD.
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Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling.
TL;DR: The preclinical study suggests that hesperetin conferred neuroprotection by regulating the TLR4/NF-κB signaling pathway against the detrimental effects of LPS.
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Neuroprotective Effect of Quercetin Against the Detrimental Effects of LPS in the Adult Mouse Brain.
Amjad Khan,Tahir Ali,Shafiq Ur Rehman,Muhammad Sohail Khan,Sayed Ibrar Alam,Muhammad Ikram,Tahir Muhammad,Kamran Saeed,Haroon Badshah,Myeong Ok Kim +9 more
TL;DR: It is demonstrated that natural flavonoids such as quercetin can be beneficial against LPS-induced neurotoxicity in adult mice and improved the memory performance of the L PS-treated mice.
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Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model.
TL;DR: Melatonin attenuated scopolamine-induced synaptic dysfunction and memory impairments by ameliorating oxidative brain damage, stress kinase expression, neuroinflammation, and neurodegeneration.
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Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model.
TL;DR: The neuroprotective effect of hesperetin was found to be a multipotent effect, involving the inhibition of oxidative stress, neuroinflammation, apoptotic cell death, and cognitive consolidation against Aβ-induced neurodegeneration and memory impairment.