M
Myung Hwan Lee
Researcher at Dong-a University
Publications - 13
Citations - 417
Myung Hwan Lee is an academic researcher from Dong-a University. The author has contributed to research in topics: Esterase & Gene. The author has an hindex of 9, co-authored 13 publications receiving 377 citations.
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Journal ArticleDOI
Inactivation of Chloramphenicol and Florfenicol by a Novel Chloramphenicol Hydrolase
Weixin Tao,Myung Hwan Lee,Jing Wu,Namhee Kim,Jin-Cheol Kim,Eunsook Chung,Eul Chul Hwang,Seon-Woo Lee +7 more
TL;DR: This is the first report of enzymatic hydrolysis of florfenicol resulting in inactivation of the antibiotic.
Journal ArticleDOI
Forest soil metagenome gene cluster involved in antifungal activity expression in Escherichia coli.
Eu Jin Chung,Eu Jin Chung,He Kyoung Lim,Jin-Cheol Kim,Gyung Ja Choi,Eun Jin Park,Myung Hwan Lee,Young Ryun Chung,Seon-Woo Lee +8 more
TL;DR: The first report of an antifungal gene cluster obtained from a soil metagenome using Saccharomyces cerevisiae as a target fungus is reported, suggesting the metagenomic approach as an alternative to search for novel antIFungal antibiotics from unculturable soil bacteria.
Journal ArticleDOI
Bioprospecting Potential of the Soil Metagenome: Novel Enzymes and Bioactivities
Myung Hwan Lee,Seon-Woo Lee +1 more
TL;DR: This review summarizes the microbial diversity in soils and the efforts to search for microbial resources from the soil metagenome, with more emphasis on the potential of bioprospecting metagenomics and recent discoveries.
Journal ArticleDOI
A new esterase EstD2 isolated from plant rhizosphere soil metagenome
Myung Hwan Lee,Kyung Sik Hong,Shweta Malhotra,Ji Hye Park,Eul Chul Hwang,Hong Kyu Choi,Young Sup Kim,Weixin Tao,Seon-Woo Lee +8 more
TL;DR: Phylogenetic analysis revealed that the lipolytic protein EstD2 may be a member of a novel family oflipolytic enzymes and suggested that the other hypothetical protein homologs of EstD 2 might also be members of this novel family.
Journal Article
Selection and characterization of forest soil metagenome genes encoding lipolytic enzymes
Kyung Sik Hong,He Kyoung Lim,Eu Jin Chung,Eun Jin Park,Myung Hwan Lee,Jin-Cheol Kim,Gyung Ja Choi,Kwang Yun Cho,Seon-Woo Lee +8 more
TL;DR: A forest soil metagenomic library using a fosmid and soil microbial DNA from Gwangneung forest, Korea, was constructed in Escherichia coli and screened to select lipolytic genes, revealing that 4 genes encode hormone-sensitive lipase (HSL) in lipase family IV and a GDSL enzyme is the first description of the enzyme from meetagenomic screening.