THE DESIGN AND ANALYSIS OF EXPERIMENTS. By Oscar Kempthorne. New York, John Wiley and Sons, Inc., 1952. 631 pp. $8.50. This book by a teacher of statistics (as well as a consultant for \"experimenters\") is a comprehensive study of the philosophical background for the statistical design of experiment. It is necessary to have some facility with algebraic notation and manipulation to be able to use the volume intelligently. The problems are presented from the theoretical point of view, without such practical examples as would be helpful for those not acquainted with mathematics. The mathematical justification for the techniques is given. As a somewhat advanced treatment of the design and analysis of experiments, this volume will be interesting and helpful for many who approach statistics theoretically as well as practically. With emphasis on the \"why,\" and with description given broadly, the author relates the subject matter to the general theory of statistics and to the general problem of experimental inference. MARGARET J. ROBERTSON

The Design and Analysis of Experiments

Parametric appraisal of mechanical property of fused deposition modelling processed parts

3D printing, more formally known as Additive Manufacturing (AM), is already being adopted for rapid prototyping and soon rapid manufacturing. This review provides a brief discussion about AM and also the most employed AM technologies for polymers. The commonly-used ASTM and ISO mechanical test standards which have been used by various research groups to test the strength of the 3D-printed parts have been reported. Also, a summary of an exhaustive amount of literature regarding the mechanical properties of 3D-printed parts is included, specifically, properties under different loading types such as tensile, bending, compressive, fatigue, impact and others. Properties at low temperatures have also been discussed. Further, the effects of fillers as well as post-processing on the mechanical properties have also been discussed. Lastly, several important questions to consider in the standardization of mechanical test methods have been raised.

Mechanical characterization of 3D-printed polymers

https://isiarticles.com/bundles/Article/pre/pdf/7398.pdf

A discrete artificial bee colony algorithm for the lot-streaming flow shop scheduling problem

The recent introduction of the first FDA approved 3D-printed drug has fuelled interest in 3D printing technology, which is set to revolutionize healthcare. Since its initial use, this rapid prototyping (RP) technology has evolved to such an extent that it is currently being used in a wide range of applications including in tissue engineering, dentistry, construction, automotive and aerospace. However, in the pharmaceutical industry this technology is still in its infancy and its potential yet to be fully explored. This paper presents various 3D printing technologies such as stereolithographic, powder based, selective laser sintering, fused deposition modelling and semi-solid extrusion 3D printing. It also provides a comprehensive review of previous attempts at using 3D printing technologies on the manufacturing dosage forms with a particular focus on oral tablets. Their advantages particularly with adaptability in the pharmaceutical field have been highlighted, which enables the preparation of dosage forms with complex designs and geometries, multiple actives and tailored release profiles. An insight into the technical challenges facing the different 3D printing technologies such as the formulation and processing parameters is provided. Light is also shed on the different regulatory challenges that need to be overcome for 3D printing to fulfil its real potential in the pharmaceutical industry.

/pdf/emergence-of-3d-printed-dosage-forms-opportunities-and-4jnzvtjk1k.pdf

Emergence of 3D Printed Dosage Forms: Opportunities and Challenges

A hybrid cuckoo search and genetic algorithm for reliability-redundancy allocation problems

Purpose – Mechanical properties such as tensile, yield, impact strengths, and development of residual stresses play an important role intooling applications. The objective of this paper is to investigate the effect of layer thickness – one of the influential process parameters in stereolithography (SL) process, on mechanical properties of SL components.Design/methodology/approach – Test specimens are constructed as per the ASTM standards for different layer thicknesses in SL 5000 machine, using epoxy resin CIBA tool ® SL5530, a high temperature resistant SL material that is suitable for rapid tooling applications. Tensile, yield and impact tests are carried out with suitable equipments. Residual stress is analysed using hole drill method.Findings – The analysis reveals that when the layer thickness is smaller, the strength of the part is higher.Research limitations/implications – Conclusion of this research is drawn based on the analysis of the most widely used three layer thicknesses of 100, 125 and 150 ...

Influence of layer thickness on mechanical properties in stereolithography

A genetic algorithm for optimal operating parameters of VMI system in a two-echelon supply chain

A genetic algorithm for the two-stage supply chain distribution problem associated with a fixed charge

Industrial robots, due to their great speed, precision and cost-effectiveness in repetitive tasks, now tend to be used in place of human workers in automated manufacturing systems. In particular, they perform the pick-and-place operation, a non-value-added activity which at the same time cannot be eliminated. Hence, minimum time is an important consideration for economic reasons in the trajectory planning system of the manipulator. The trajectory should also be smooth to handle parts precisely in applications such as semiconductor manufacturing, processing and handling of chemicals and medicines, and fluid and aerosol deposition. In this paper, an automated trajectory planner is proposed to determine a smooth, minimum-time and collision-free trajectory for the pick-and-place operations of a 6-DOF robotic manipulator in the presence of an obstacle. Subsequently, it also proposes an algorithm for the jerk- bounded Synchronized Trigonometric S-curve Trajectory (STST) and the 'forbidden-sphere' technique to avoid the obstacle. The proposed planner is demonstrated with suitable examples and comparisons. The experiments show that the proposed planner is capable of providing a smoother trajectory than the cubic spline based trajectory.

N. Jawahar

Papers

A hybrid cuckoo search and genetic algorithm for reliability-redundancy allocation problems

Influence of layer thickness on mechanical properties in stereolithography

A genetic algorithm for optimal operating parameters of VMI system in a two-echelon supply chain

A genetic algorithm for the two-stage supply chain distribution problem associated with a fixed charge

Automated Trajectory Planner of Industrial Robot for Pick-and-Place Task: