N
N Mavaddat
Researcher at University of Oxford
Publications - 2
Citations - 326
N Mavaddat is an academic researcher from University of Oxford. The author has contributed to research in topics: Protein–protein interaction & Semaphorin. The author has an hindex of 2, co-authored 2 publications receiving 314 citations. Previous affiliations of N Mavaddat include University of Cambridge.
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Journal ArticleDOI
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
Christopher Love,Karl Harlos,N Mavaddat,N Mavaddat,Simon J. Davis,David I. Stuart,E Y Jones,Robert Esnouf +7 more
TL;DR: The crystal structure of SEMA4D shows the sema topology to be a seven-bladed β-propeller, revealing an unexpected homology with integrins.
Journal ArticleDOI
Signaling lymphocytic activation molecule (CDw150) is homophilic but self-associates with very low affinity.
N Mavaddat,D. W. Mason,P D Atkinson,Edward J. Evans,Robert J.C. Gilbert,Robert J.C. Gilbert,David I. Stuart,David I. Stuart,J A Fennelly,A N Barclay,Simon J. Davis,Marion H. Brown +11 more
TL;DR: Surface plasmon resonance-based methods and analytical ultracentrifugation data indicate that SLAM-SLAM interactions are in fact considerably weaker than most other well characterized protein-protein interactions at the cell surface, which raises important questions regarding the physiological role and/or properties of such interactions.