N
Nadya Abbood
Researcher at Goethe University Frankfurt
Publications - 5
Citations - 39
Nadya Abbood is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Computer science & Biology. The author has an hindex of 2, co-authored 3 publications receiving 5 citations. Previous affiliations of Nadya Abbood include Max Planck Society.
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Synthetic Zippers as an Enabling Tool for Engineering of Non-Ribosomal Peptide Synthetases*.
TL;DR: In this paper, a cloning and co-expression strategy was described to functionally combine NRPS fragments of Gram-negative and -positive origin, synthesising novel peptides at titres up to 220 mg l -1.
Posted ContentDOI
Synthetic Zippers as an Enabling Tool for Engineering of Non-Ribosomal Peptide Synthetases
TL;DR: This work describes a strategy to functionally combine NRPS fragments of Gram-negative and -positive origin, synthesising novel peptides at titres up to 290 mg l-1, and inserts synthetic zippers to split single protein NRPSs into up to three independently expressed and translated polypeptide chains.
Posted ContentDOI
Guidelines for Optimizing Type S Non-Ribosomal Peptide Synthetases
TL;DR: In this paper , an artificial synthetic non-ribosomal peptide synthetases (NRPS) type, referred to as type S NRPS, was introduced to provide a first-of-its-kind bicombinatorial approach to parallelized high-throughput NRP library generation.
Posted ContentDOI
Type S Non Ribosomal Peptide Synthetases for the rapid generation of tailor-made peptide libraries
Nadya Abbood,Nadya Abbood,Tien Duy Vo,Jonas Watzel,Kenan A. J. Bozhueyuek,Kenan A. J. Bozhueyuek,Helge B. Bode,Helge B. Bode +7 more
TL;DR: In this article, a proof-of-principle study on generating bipartite type S non-ribosomal peptide synthetases (NRPSs) on an unreached scale is presented.