Showing papers by "Nancy Carney published in 2011"
TL;DR: Patients who responded to ICP-lowering treatment had a 64% lower risk of death at 2 weeks than those who did not respond after adjusting for factors that independently predictrisk of death.
Abstract: Object The normalization of increased intracranial pressure (ICP) in patients with severe traumatic brain injury (TBI) is assumed to limit secondary brain injury and improve outcome Despite evidence-based recommendations for monitoring and treatment of elevated ICP, there are few studies that show an association between response to ICP-directed therapeutic regimens and adjusted mortality rate This study utilizes a large prospective database to examine the effect of response to ICP-lowering therapy on risk of death within the first 2 weeks of injury in patients who sustained TBI and are older than 16 years Methods The current study is based on 1426 patients with severe TBI (Glasgow Coma Scale [GCS] score 25 mm Hg) between 2000 and 2008 at 22 trauma centers enrolled in a New York State quality improvement program This prospectively collected database also contains information including age, admission GCS score, pupillary status, CT scanning parameters, a
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