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Nancy L. Young
Researcher at Centers for Disease Control and Prevention
Publications - 26
Citations - 2935
Nancy L. Young is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Population & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 23, co-authored 26 publications receiving 2906 citations. Previous affiliations of Nancy L. Young include Thailand Ministry of Public Health.
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Journal ArticleDOI
Short-course zidovudine for perinatal HIV-1 transmission in Bangkok, Thailand: a randomised controlled trial
Nathan Shaffer,Rutt Chuachoowong,Philip A. Mock,Chaiporn Bhadrakom,Wimol Siriwasin,Nancy L. Young,Tawee Chotpitayasunondh,Sanay Chearskul,Anuvat Roongpisuthipong,Pratharn Chinayon,John M. Karon,Timothy D. Mastro,R.J. Simonds +12 more
TL;DR: A short course of twice-daily oral zidovudine was safe and well tolerated and, in the absence of breastfeeding, can lessen the risk for mother-to-child HIV-1 transmission by half.
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Independent introduction of two major HIV-1 genotypes into distinct high-risk populations in Thailand
Chin-Yih Ou,Bruce G. Weniger,Chi-Cheng Luo,Marcia L. Kalish,Gayle Hd,Nancy L. Young,Gerald Schochetman,Y. Takebe,Shudo Yamazaki,W. Auwanit +9 more
TL;DR: The findings suggest that the waves of HIV-1 infection in injecting drug users and in sexually infected patients in Thailand may not be epidemiologically linked, and nucleotide divergence data point to the separate introductions of the two genotypes in Thailand.
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Intersubtype Human Immunodeficiency Virus Type 1 Superinfection following Seroconversion to Primary Infection in Two Injection Drug Users
Artur Ramos,Dale J. Hu,Lily Nguyen,Kim Oanh Phan,Suphak Vanichseni,Nattawan Promadej,Kachit Choopanya,Margaret E. Callahan,Nancy L. Young,Janet M. McNicholl,Timothy D. Mastro,Thomas M. Folks,Shambavi Subbarao +12 more
TL;DR: The data show that, in some individuals, the quality and quantity of the immune response elicited by primary HIV-1 infection may not protect against superinfection, which has important implications for vaccine design.
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Maternal viral load and timing of mother-to-child HIV transmission Bangkok Thailand.
Philip A. Mock,Nathan Shaffer,Chaiporn Bhadrakom,Wimol Siriwasin,Tawee Chotpitayasunondh,Sanay Chearskul,Nancy L. Young,Anuvat Roongpisuthipong,Pratharn Chinayon,Marcia L. Kalish,Bharat Parekh,Timothy D. Mastro +11 more
TL;DR: The results provide further evidence that most perinatal HIV-1 transmission occurs during labor and delivery, and that risk factors may differ according to time of transmission.
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Continued high HIV-1 incidence in a vaccine trial preparatory cohort of injection drug users in Bangkok, Thailand.
Suphak Vanichseni,Dwip Kitayaporn,Timothy D. Mastro,Timothy D. Mastro,Philip A. Mock,Suwanee Raktham,Don C. Des Jarlais,Sathit Sujarita,La Ong Srisuwanvilai,Nancy L. Young,Chantapong Wasi,Shambavi Subbarao,William L. Heyward,William L. Heyward,José Esparza,Kachit Choopanya +15 more
TL;DR: HIV-1 transmission risk remains high among Bangkok IDUs despite methadone treatment and other current prevention strategies, and this study led to the initiation in 1999 of a phase III HIV-1 vaccine efficacy trial in this population.