Naomi C. Green

TL;DR: This review aims to provide an update on the current status of AM to mimic the mechanical properties of CTs, with focus on arterial tissue, articular cartilage and bone, from the perspective of printing platforms, biomaterial properties, and topological design.

TL;DR: The reduced opening area of a bicuspid aortic valve amplifies any impaired hemodynamics, but cusp orientation determines subsequent flow patterns which may determine the specific regions downstream from the valve most at risk of clinical complications.

TL;DR: Overall, whilst side-holes may be associated with increased clotting and infection, this can be reduced when side-hole geometry is correctly implemented though; a sufficient area for body diameter and utilising angle-cut, oval shaped holes (reducing shear stress and chances of fibrin formation partially occluding holes).

TL;DR: A method for measuring the low volumetric wear expected in ceramic total disc replacements, which can be used to replace intervertebral discs in the spine, using non-contacting optical methods and could be applied to more severe wear, other types of orthopaedic implants and different materials.

TL;DR: The findings of this proof-of-concept work suggest that there are specific differences across haemodynamics and valve mechanics associated with BAV phenotypes, which may be critical to subsequent processes associated with their pathophysiology processes.