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Naomi J. Walker

Researcher at University of California, Davis

Publications -  68
Citations -  3135

Naomi J. Walker is an academic researcher from University of California, Davis. The author has contributed to research in topics: Mesenchymal stem cell & Bone marrow. The author has an hindex of 29, co-authored 67 publications receiving 2761 citations. Previous affiliations of Naomi J. Walker include University of Minnesota & University of California, Berkeley.

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Human platelets loaded with trehalose survive freeze-drying.

TL;DR: It is reported here that platelets can be preserved by freeze-drying them with trehalose, a sugar found at high concentrations in organisms that naturally survive drying, and suggested that these findings will obviate the storage problem with platelets.
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Evaluation of senescence in mesenchymal stem cells isolated from equine bone marrow, adipose tissue, and umbilical cord tissue.

TL;DR: The results demonstrate the limited passage numbers of subcultured BMSCs available for use in research and tissue engineering and suggest that adipose tissue and umbilical cord tissue may be preferable for tissue banking purposes.
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Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells

TL;DR: Activated equine MSCs derived from BM, AT, CT, and CB secrete high concentration of mediators and are similar to M SCs from rodents and humans in their immunomodulatory profiles, which have implication for the treatment of inflammatory lesions dominated by activated lymphocytes and TNF-α and IFN-γ in vivo.
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Membrane phase transition of intact human platelets: Correlation with cold‐induced activation

TL;DR: This work suggests that AFGPs may be a possible solute for use in long‐term low temperature storage of platelets, and incubating platelets with antifreeze glycoproteins during long‐ term storage and rapid rewarming to 37°C abrogated granule secretion associated with cold activation in a dose‐dependent manner.
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Clinicopathologic findings following intra-articular injection of autologous and allogeneic placentally derived equine mesenchymal stem cells in horses.

TL;DR: The healthy equine joint responds similarly to a single intra-articular injection of autologous and allogeneic MSC, and this pre-clinical safety study is an important first step in the development of equineAllogeneic stem cell therapies.