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Naomi Todd
Researcher at Queen's University Belfast
Publications - 6
Citations - 78
Naomi Todd is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: FKBPL & Preeclampsia. The author has an hindex of 3, co-authored 6 publications receiving 43 citations.
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Journal ArticleDOI
Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair
Nicola Fergie,Naomi Todd,Lana McClements,Daniel F. McAuley,Cecilia O'Kane,Anna Krasnodembskaya +5 more
TL;DR: It is demonstrated that HCA attenuates the inflammatory response and reparative potential of primary human small airway epithelial and capillary endothelium and induces mitochondrial dysfunction and mesenchymal stem cells promote lung epithelial wound repair via the transfer of functional mitochondria.
Journal ArticleDOI
Role of A Novel Angiogenesis FKBPL-CD44 Pathway in Preeclampsia Risk Stratification and Mesenchymal Stem Cell Treatment.
Naomi Todd,Ross McNally,Abdelrahim Alqudah,Abdelrahim Alqudah,Djurdja Jerotic,Sonja Suvakov,Sonja Suvakov,Danilo Obradovic,Denise Hoch,Jose R. Hombrebueno,Guillermo Lopez Campos,Chris J Watson,Miroslava Gojnic-Dugalic,Tatjana Simic,Anna Krasnodembskaya,Gernot Desoye,Kelly-Ann Eastwood,Kelly-Ann Eastwood,Alyson Hunter,Valerie Holmes,David R. McCance,David R. McCance,Ian S. Young,Ian S. Young,David J. Grieve,Louise C. Kenny,Louise C. Kenny,Vesna D. Garovic,Tracy Robson,Lana McClements,Lana McClements +30 more
TL;DR: The FKBPL-CD44 pathway appears to have a central role in the pathogenesis of preeclampsia, showing promising utilities for early diagnostic and therapeutic purposes.
Journal ArticleDOI
FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function.
Abdelrahim Alqudah,Kelly-Ann Eastwood,Djurdja Jerotic,Naomi Todd,Denise Hoch,Ross McNally,Danilo Obradovic,Stefan Dugalic,Alyson Hunter,Valerie Holmes,David R. McCance,David R. McCance,Ian S. Young,Ian S. Young,Chris J Watson,Tracy Robson,Gernot Desoye,David J. Grieve,Lana McClements,Lana McClements +19 more
TL;DR: In this paper, the role of FKBPL and SIRT-1 in pre-gestational (type 1 diabetes mellitus, T1D) and gestational Diabetes mellitus (GDM) was investigated.
Posted ContentDOI
FKBPL and SIRT-1, key angiogenesis proteins, are downregulated by diabetes in pregnancy
Abdelrahim Alqudah,Abdelrahim Alqudah,Kelly-Ann Eastwood,Kelly-Ann Eastwood,Djurdja Jerotic,Naomi Todd,Denise Hoch,Ross McNally,Danilo Obradovic,Stefan Dugalic,Alyson Hunter,Valerie Holmes,David R. McCance,David R. McCance,Ian S. Young,Ian S. Young,Chris J Watson,Tracy Robson,Gernot Desoye,David J. Grieve,Lana McClements,Lana McClements +21 more
TL;DR: FKBPL and/or SIRT-1 downregulation in response to diabetes may have a role in the development of vascular dysfunction in pregnancy, and associated complications such as preeclampsia.
Proceedings ArticleDOI
6 The role of a novel angiogenesis related protein, FKBPL, in spiral uterine artery remodelling important for the pathogenesis of preeclampsia
TL;DR: In vitro data suggest that FKBPL plays an important role in trophoblast functionality, which may extend to spiral uterine artery remodelling underlying the pathogenesis of pre-eclampsia.