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Natalia Díez-Revuelta
Publications - 8
Citations - 200
Natalia Díez-Revuelta is an academic researcher. The author has contributed to research in topics: Axon & Myelin. The author has an hindex of 6, co-authored 7 publications receiving 174 citations.
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Journal ArticleDOI
Neuronal Galectin-4 is required for axon growth and for the organization of axonal membrane L1 delivery and clustering.
Silvia Velasco,Natalia Díez-Revuelta,Teresa Hernández-Iglesias,Herbert Kaltner,Sabine André,Hans-Joachim Gabius,José Abad-Rodríguez +6 more
TL;DR: Galectin-4 (Gal-4) is expressed by hippocampal and cortical neurons where it is sorted to discrete segments of the axonal membrane in a microtubule-and sulfatide-dependent manner.
Journal ArticleDOI
Phosphorylation of adhesion- and growth-regulatory human galectin-3 leads to the induction of axonal branching by local membrane L1 and ERM redistribution.
Natalia Díez-Revuelta,Silvia Velasco,Sabine André,Herbert Kaltner,Dieter Kübler,Hans-Joachim Gabius,José Abad-Rodríguez +6 more
TL;DR: It is proposed that the local regulation of the L1-ERM-actin pathway, at the level of the plasma membrane, underlies pGal-3-induced axon branching, and that galectin phosphorylation in situ could act as a molecular switch for the axon response to Gal-3.
Journal ArticleDOI
The sugar code in neuronal physiology.
TL;DR: The roles of glycans in neuroscience are far from being completely understood, though the cases presented here underscore the importance and potential of carbohydrates to establish with precision key molecular mechanisms of the physiology of the nervous system.
Journal ArticleDOI
Neurons define non-myelinated axon segments by the regulation of galectin-4-containing axon membrane domains
Natalia Díez-Revuelta,Alonso M. Higuero,Silvia Velasco,Maria Penas-de-la-Iglesia,Hans-Joachim Gabius,José Abad-Rodríguez +5 more
TL;DR: It is reported here that oligodendrocytes (OLGs) do not deposit myelin on Gal-4 covered surfaces or myelinate axonal G4Ds, andGal-4 is sorted to segmental domains (G4Ds) along the axon surface, reminiscent of these long unmyelinated axon segments in cortical neurons.
Journal ArticleDOI
Axon glycoprotein routing in nerve polarity, function, and repair
TL;DR: Deciphering the details of the glycan structures and carbohydrate-binding molecules that underlie these mechanisms improves the knowledge of nerve physiology and defines novel specific approaches for neurological treatments.