Natalia K. Botelho

TL;DR: VAT in T2D expresses higher levels of adipokines involved in inflammation, which may explain the links observed between visceral obesity, insulin resistance, and diabetes risk.

TL;DR: It is speculated that immune inflammation occurring in Barrett's esophagus alters the mucosal microenvironment in a manner which is favorable to the activation of dormant stem cells.

TL;DR: FTO gene expression is not increased in SAT and VAT in T2D and does not relate to insulin action, and the links between FTO and metabolic complications of diabetes require further elucidation.

TL;DR: In morbidly obese dysglycaemic subjects, modest weight loss reduces arterial stiffness, the magnitude of which relates to improved markers of inflammation.

TL;DR: Investigation of the effectiveness of HSV-tk activation as gene therapy for gastroesophageal junction and gastric adenocarcinomas using either the stress-inducible Grp78 promoter or the murine leukemia virus long-terminal repeat (LTR) promoter found the most effective approach used the Grp 78 promoter in glucose-starvation stress conditions.