Natalia Spinella

TL;DR: The present work aims to demonstrate the great potential that exists by combining an optimized reflective substrate with a high performance surface chemistry and the techniques chosen for both the substrate and surface chemistry are simple, inexpensive, and amenable to mass production.

TL;DR: In vivo studies in a transgenic Caenorhabditis elegans strain expressing human Aβ indicated that silybin B is the most effective of the four compounds in counteracting Aβ proteotoxicity, and this study underscores the pivotal role of stereochemistry in determining the neuroprotective potential of silybins.

TL;DR: In this paper, the morphological and chemical changes undergone by the surface during the treatment are studied ex situ (via x-ray-photoelectron spectroscopy, atomic force microscopy, scanning tunneling microscopy and infrared absorption spectrographic in the attenuated total reflection mode, reflection high-energy electron diffraction, and thermal programmed desorption) and the mechanisms responsible for them are discussed.

TL;DR: It is demonstrated that conjugation of a trehalose moiety to silybin significantly increases both water solubility and stability in blood serum without significantly compromising its anti-aggregation properties.

TL;DR: In this article, a photodiode is formed by a body of semiconductor material having a first surface, an integrated optical structure on the first surface and having a second surface, and at least one detection region on the second surface.