Nathan L. Pace

TL;DR: In this paper, the authors evaluated the impact of a new therapy that includes pressure-controlled inverse ratio ventilation followed by extracorporeal CO2 removal on the survival of patients with severe ARDS in a randomized controlled clinical trial.

TL;DR: It is concluded that there was no significant difference in survival between the mechanical ventilation and the extracorporeal CO2 removal groups, and extracordoreal support for ARDS should be restricted to controlled clinical trials.

TL;DR: Combining midazolam with fentanyl or other opioids produces a potent drug interaction that places patients at a high risk for hypoxemia and apnea, andequate precautions are recommended when benzodiazepines are administered in combination with opioids.

TL;DR: The acquisition of pneumonia by a low-risk patient should alert the physician to the possibility of a potentially preventable nosocomial infection.

TL;DR: The up-and-down method of Dixon and Mood is now commonly used in anesthesia research as mentioned in this paper, which allows the design of experiments for the measurement of the response at any point (quantile) along the dose-response curve, demonstrate the risk of certain statistical methods commonly used by literature reports, and allow the estimation of the concentration or dose associated with the chosen quantile without the assumption of the symmetry of the tolerance distribution.