N
Nebiyu Osman
Researcher at University of Pennsylvania
Publications - 1
Citations - 616
Nebiyu Osman is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Pioneer factor & Zinc finger. The author has an hindex of 1, co-authored 1 publications receiving 487 citations.
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Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming
Abdenour Soufi,Meilin Fernandez Garcia,Artur Jaroszewicz,Nebiyu Osman,Matteo Pellegrini,Kenneth S. Zaret +5 more
TL;DR: This work compares the nucleosome and chromatin targeting activities of Oct4, Sox2, and Klf4, which together reprogram somatic cells to pluripotency and provides insight into how pioneer factors can target naive chromatin sites.