N
Neelakantan Saikrishnan
Researcher at Georgia Institute of Technology
Publications - 50
Citations - 1056
Neelakantan Saikrishnan is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: Aortic valve & Mitral valve. The author has an hindex of 18, co-authored 50 publications receiving 946 citations. Previous affiliations of Neelakantan Saikrishnan include University of Minnesota & The Wallace H. Coulter Department of Biomedical Engineering.
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Experimental measurement of dynamic fluid shear stress on the aortic surface of the aortic valve leaflet.
TL;DR: This study characterizes AV leaflet aortic surface fluid shear stresses using Laser Doppler velocimetry and an in vitro pulsatile flow loop and represents the most well-resolved shear stress measurements to date across a range of conditions on the aorta side of the AV.
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Accurate Assessment of Aortic Stenosis: A Review of Diagnostic Modalities and Hemodynamics
TL;DR: Aortic valve (AV) stenosis is one of the most common valvular diseases and is the third most common cardiovascular disease in developed countries and without intervention, patient mortality typically occurs within 5 years of the onset of symptoms.
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In Vitro Characterization of Bicuspid Aortic Valve Hemodynamics Using Particle Image Velocimetry
Neelakantan Saikrishnan,Choon Hwai Yap,Nicole C. Milligan,Nikolay V. Vasilyev,Ajit P. Yoganathan +4 more
TL;DR: The in vitro model described here enables detailed characterization of BAV flow characteristics, which is currently challenging in clinical practice and can prove to be useful in studying the effects of altered BAV geometry on fluid dynamics in the valve and ascending aorta.
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An In Vitro Evaluation of the Impact of Eccentric Deployment on Transcatheter Aortic Valve Hemodynamics
TL;DR: The results of this study indicate that eccentric deployment of TAVRs can lead to altered flow characteristics and may potentially increase the hemolytic potential of the valve, which were not captured through hemodynamic evaluation alone.
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A Novel Left Heart Simulator for the Multi-modality Characterization of Native Mitral Valve Geometry and Fluid Mechanics
TL;DR: This work represents the first comprehensive database of high fidelity experimental data, critical for extensive validation of mitral valve fluid structure interaction simulations, designed specifically for the validation of numerical Mitral valve models.