Biology of Incretins: GLP-1 and GIP

Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in the intestinal epithelial endocrine L-cells by differential processing of proglucagon, the gene which is expressed in ...

The Physiology of Glucagon-like Peptide 1

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1053/he.2000.5852

A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts.

https://www.journal-of-hepatology.eu/article/S0168-8278(05)00684-7/pdf

Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies.

https://www.gastrojournal.org/article/S0016-5085(04)01593-8/pdf

Hepatocellular carcinoma in cirrhosis: incidence and risk factors.

New interpretation of oral glucose tolerance

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.1840190104

Hepatitis C Virus Genotypes: An Investigation of Type-specific Differences in Geographic Origin and Disease

Arterial blood glucose and plasma insulin levels following intrajejunal infusion of glucose were compared with those obtained after intravenous infusion of glucose at the same rate. Despite the lower blood glucose levels there was a much higher plasma insulin response to glucose given jejunally than to glucose given intravenously. Rapid administration of glucose by both routes led to an exaggeration of the inverse relationship between the blood glucose and plasma insulin levels. Similar results were obtained in 2 patients with cirrhosis of the liver who had had end-to-side portacaval shunts performed. Possible explanations of these findings are discussed and reasons are given for believing that a humoral substance is released from the jejunal wall during glucose absorption which acts by stimulating the release of insulin from the pancreatic islet cells.

Intestinal Factors in the Control of Insulin Secretion

https://www.gastrojournal.org/article/0016-5085(90)91166-4/pdf

Randomized, double-blind, placebo-controlled trial of somatostatin for variceal bleeding : emergency control and prevention of early variceal rebleeding

Neil McIntyre

Papers

New interpretation of oral glucose tolerance

Hepatitis C Virus Genotypes: An Investigation of Type-specific Differences in Geographic Origin and Disease

Intestinal Factors in the Control of Insulin Secretion

Randomized, double-blind, placebo-controlled trial of somatostatin for variceal bleeding : emergency control and prevention of early variceal rebleeding

Decreased erythrocyte membrane fluidity and altered lipid composition in human liver disease