D. Brown

TL;DR: The data suggest significant geographic clustering of type 4 disease in the Middle East area and poor response to interferon‐α was noted in patients with type 1 disease, which may have important clinical implications.

TL;DR: It is concluded that a characteristic histological pattern exists in chronic hepatitis C, that this pattern is not always found and that prominent lymphoid follicles, though not unique to hepatitisC, provide a useful diagnostic clue.

TL;DR: It is found that the profiles of virus-specific CD8+-T-cell responses during chronic infections are highly heterogeneous and influenced more by the level of HBV replication than by the activity of liver disease.

TL;DR: An international phylogenetic study revealed a large international network of HCV transmission among HIV-positive MSM, supported by the large proportion of European MSM infected with an HCV strain co-circulating in multiple European countries, the low evolutionary distances among HCV isolates from different countries, and the trend toward increased country mixing with increasing cluster size.

TL;DR: It is concluded that HCV is a major cause of chronic hepatitis in patients with thalassaemia major and is associated with raised AST activity and serum ferritin concentration compared with patients seronegative for anti-HCV.