N
Nicole E.C. van Klink
Researcher at Utrecht University
Publications - 26
Citations - 859
Nicole E.C. van Klink is an academic researcher from Utrecht University. The author has contributed to research in topics: Epilepsy & Medicine. The author has an hindex of 11, co-authored 20 publications receiving 571 citations. Previous affiliations of Nicole E.C. van Klink include Montreal Neurological Institute and Hospital & University Medical Center Utrecht.
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Journal ArticleDOI
Residual fast ripples in the intraoperative corticogram predict epilepsy surgery outcome
Maryse A. van 't Klooster,Nicole E.C. van Klink,Frans S. S. Leijten,Rina Zelmann,Tineke A. Gebbink,Peter H. Gosselaar,Kees P.J. Braun,Geertjan Huiskamp,Maeike Zijlmans +8 more
TL;DR: Residual FRs in post-resection intraoperative electrocorticography (ECoG) are prognostic markers for seizure recurrence, especially if their number is high, and Tailoring could rely on FRs, but requires careful assessment of the ECoG, asFRs in functionally eloquent areas might not be pathologic.
Journal ArticleDOI
Changing concepts in presurgical assessment for epilepsy surgery
TL;DR: The importance of looking beyond the EEG seizure onset zone and considering focal epilepsy as a brain network disease in which long-range connections need to be taken into account is highlighted, and how new diagnostic techniques are revealing essential information in the brain that was previously hidden from view is explored.
Journal ArticleDOI
Tailoring epilepsy surgery with fast ripples in the intraoperative electrocorticogram
Maryse A. van 't Klooster,Nicole E.C. van Klink,Willemiek J. E. M. Zweiphenning,Frans S. S. Leijten,Rina Zelmann,Cyrille H. Ferrier,Peter C. van Rijen,Willem M. Otte,Kees P.J. Braun,Geertjan Huiskamp,Maeike Zijlmans +10 more
TL;DR: High‐frequency oscillations (HFOs) seem better biomarkers for epileptogenic tissue than spikes in combined pre‐ and postresection ECoG predict surgical outcome in different tailoring approaches.
Journal ArticleDOI
Ripples on rolandic spikes : A marker of epilepsy severity
Nicole E.C. van Klink,Maryse A. van 't Klooster,Frans S. S. Leijten,Julia Jacobs,Kees P.J. Braun,Maeike Zijlmans +5 more
TL;DR: This work investigated whether ripples (80–250 Hz), superimposed on rolandic spikes in surface electroencephalography (EEG) can differentiate between different entities.
Journal ArticleDOI
Automatic detection of high frequency oscillations during epilepsy surgery predicts seizure outcome
Tommaso Fedele,Maryse A. van 't Klooster,Sergey Burnos,Sergey Burnos,Willemiek J. E. M. Zweiphenning,Nicole E.C. van Klink,Frans S. S. Leijten,Maeike Zijlmans,Johannes Sarnthein +8 more
TL;DR: The authors' automatic and fully unsupervised detection of HFO events matched the expert observer's performance in both event selection and outcome prediction.