Recent advances in guar gum based drug delivery systems and their administrative routes.

In this study, seaweed polysaccharides (alginate and carrageenan) were modified with dodecenylsuccinic anhydride (DSA), and their stabilising properties in oil‐in‐water (O/W) emulsion system were evaluated. The physicochemical characteristics were determined by droplet size, interfacial tension and ζ‐potential and structurally verified by Fourier transform infrared spectroscopy (FTIR). Both CRG‐DSA and ALG‐DSA applied in O/W emulsion system exhibited smaller droplet sizes over the increasing concentration and were more stable during storage than native ones. The ζ‐potential of DSA‐modified seaweed polysaccharides has more negative charge compared with their native forms, owing to the additional carboxyl groups from modification reaction. In addition, DSA‐modified seaweed polysaccharides decreased the interfacial tension at soybean oil–water interface from 23.1 and 23.9 mN m⁻¹ to 14.2 and 13.6 mN m⁻¹, respectively. The successful modification reaction was confirmed by FTIR analysis. This study demonstrated that DSA‐modified seaweed polysaccharides may serve as prospective emulsifiers in food, pharmaceutical and other industrial fields.

Formulation and characterisation of O/W emulsions stabilised with modified seaweed polysaccharides

Cashew gum (CG) shows promise of being useful as an agro-based raw material for the production of eco-friendly and biodegradable polymers. In this work, we modified this water-soluble polymer with alkenyl succinic anhydride in order to attach a hydrophobic group to it. The modification used two reagents: octenyl succinic anhydride and tetrapropenyl succinic anhydride. Reactions were conducted at 120 °C using dimethyl sulfoxide as a solvent, with conversions better than 88%. Samples with degrees of substitution (DS) between 0.02 and 0.20 were made. The resulting polymers were characterized using 1H NMR, 13C NMR, FTIR, TGA, and GPC. The addition of the hydrophobe decreased the affinity of cashew gum for water absorption. Hydrophobically modified polysaccharides are often used as polymeric emulsifiers, thickeners, and compatibilizers; we anticipate that these new hydrophobically modified CGs may be used for the same applications.

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Niharika Soni

Papers

Dodecenyl succinylated guar gum hydrolysate as a wall material for microencapsulation: Synthesis, characterization and evaluation