N
Nina Z. Bispham
Researcher at University of Colorado Boulder
Publications - 9
Citations - 541
Nina Z. Bispham is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Brachial artery & Arterial stiffness. The author has an hindex of 4, co-authored 9 publications receiving 342 citations. Previous affiliations of Nina Z. Bispham include Anschutz Medical Campus.
Papers
More filters
Journal ArticleDOI
Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults
Matthew J. Rossman,Jessica R. Santos-Parker,Chelsea A.C. Steward,Nina Z. Bispham,Lauren M. Cuevas,Hannah L. Rosenberg,Kayla A. Woodward,Michel Chonchol,Rachel A. Gioscia-Ryan,Michael P. Murphy,Douglas R. Seals,Douglas R. Seals +11 more
TL;DR: The findings in humans extend earlier preclinical observations and suggest that MitoQ and other therapeutic strategies targeting mitochondrial reactive oxygen species may hold promise for treating age-related vascular dysfunction.
Journal ArticleDOI
Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress
Jessica R. Santos-Parker,Talia R. Strahler,Candace J. Bassett,Nina Z. Bispham,Michel Chonchol,Douglas R. Seals +5 more
TL;DR: In healthy middle-aged and older adults, 12 weeks of curcumin supplementation improves resistance artery endothelial function by increasing vascular nitric oxide bioavailability and reducing oxidative stress, while also improving conduit artery endotheric function.
Journal ArticleDOI
Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults
Rachelle E. Kaplon,Sierra D. Hill,Nina Z. Bispham,Jessica R. Santos-Parker,Molly J. Nowlan,Laura L. Snyder,Michel Chonchol,Thomas J. LaRocca,Matthew B. McQueen,Douglas R. Seals +9 more
TL;DR: It is demonstrated that oral trehalose improves resistance artery (microvascular) function, a major risk factor for cardiovascular diseases, in MA/O adults, possibly through increasing NO bioavailability and smooth muscle sensitivity to NO.
Journal ArticleDOI
Vascular Function and Uric Acid-Lowering in Stage 3 CKD
Diana Jalal,Emily Decker,Loni Perrenoud,Kristen L. Nowak,Nina Z. Bispham,Tapan Mehta,Gerard Smits,Zhiying You,Douglas R. Seals,Michel Chonchol,Richard J. Johnson +10 more
TL;DR: Allopurinol effectively and safely lowered serum uric acid levels in adults with stage 3 CKD and asymptomatic hyperuricemia but did not improve endothelial function in this sample of patients.
Journal ArticleDOI
Inorganic Nitrite Supplementation Improves Endothelial Function With Aging: Translational Evidence for Suppression of Mitochondria-Derived Oxidative Stress.
Matthew J. Rossman,Rachel A. Gioscia-Ryan,Jessica R. Santos-Parker,Brian P. Ziemba,Kara L. Lubieniecki,Lawrence C. Johnson,Natalie E. Poliektov,Nina Z. Bispham,Kayla A. Woodward,Erzsebet E. Nagy,Nathan S. Bryan,Julie A. Reisz,Angelo D'Alessandro,Michel Chonchol,Amy L. Sindler,Douglas R. Seals +15 more
TL;DR: A randomized, placebo-controlled, parallel-group clinical trial with sodium nitrite (80 mg/day, 12 weeks) in older adults (N=49, 68±1 year) and reverse-translation experiments in young (6 months) and old (27 months) c57BL/6 mice as discussed by the authors.