Noam Shomron

TL;DR: It is shown that the expression level of two miRNAs may have valuable information that may refine stratification for patients-at-risk for relapse with CNS involvement in DLBCL, and a number of putative mechanisms for these mi RNAs regulation of CNS relapse, including neuronal plasticity and WNT signaling pathway are revealed.

TL;DR: Three functional domains of the hSlu7 protein are identified that have distinct roles in its subcellular localization: a nuclear localization signal, a zinc-knuckle motif, and a lysine-rich region, which indicates that zinc-dependent nucleocytoplasmic shuttling might be the possible molecular basis by which hSLU7 protein levels are regulated within the nucleus.

TL;DR: Screening a panel of human tissues and cell lines revealed a spliced ADAMTS13 transcript in hepatic stellate cells and a hepatoma cell line that retains the 25th intron, suggesting its biological inaccessibility may prevent its participation in regulating haemostasis and other physiologic functions.

TL;DR: This work proposes to implement three possible strategies to treat cancer as a function of disease type and state, while leveraging the advancement in materials design and in particular nanotechnology: local primary tumor abrogation, primary tumor re‐programming to prevent metastasis, and combination therapy when metastasis has already transpired.

TL;DR: It is demonstrated that in taste learning, transcription programs were activated following the physiological responses and the specific information about a given taste, and the cortical differential prolonged kinetics of mRNA following novel versus familiar taste learning may represent additional novelty related molecular response.