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Nobuko Kawasaki
Researcher at Ritsumeikan University
Publications - 26
Citations - 1032
Nobuko Kawasaki is an academic researcher from Ritsumeikan University. The author has contributed to research in topics: Epitope & C-type lectin. The author has an hindex of 13, co-authored 25 publications receiving 979 citations.
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Serum lectin with known structure activates complement through the classical pathway.
TL;DR: The activation by serum MBP was inhibited effectively by the presence of haptenic sugars and dependent absolutely upon the presenceof C4, indicating that the activation is initiated by the sugar binding activity of MBP and proceeds through the classical pathway.
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Antitumor activity of mannan-binding protein in vivo as revealed by a virus expression system: Mannan-binding proteindependent cell-mediated cytotoxicity
TL;DR: The results indicated that MBP has a previously undescribed cytotoxic activity, which is proposed to term MBP-dependent cell-mediated cytotoxicity(MDCC), which provides a model for the development of an effective and specific host defense factor for cancer gene therapy.
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Glycosylation-Dependent Interactions of C-Type Lectin DC-SIGN with Colorectal Tumor-Associated Lewis Glycans Impair the Function and Differentiation of Monocyte-Derived Dendritic Cells
Motohiro Nonaka,Bruce Yong Ma,Ryuuya Murai,Natsuko Nakamura,Makoto Baba,Nobuko Kawasaki,Keiko Hodohara,Shinji Asano,Toshisuke Kawasaki +8 more
TL;DR: It is shown that DC-SIGN is involved in the interaction of DCs with SW1116 cells through the recognition of aberrantly glycosylated forms of Lea/Leb glycans on carcinoembryonic Ag (CEA) and CEA-related cell adhesion molecule 1 (CEACAM1).
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A novel antibody for human induced pluripotent stem cells and embryonic stem cells recognizes a type of keratan sulfate lacking oversulfated structures
Keiko Kawabe,Daiki Tateyama,Hidenao Toyoda,Nana Kawasaki,Noritaka Hashii,Hiromi Nakao,Shogo Matsumoto,Motohiro Nonaka,Hiroko Matsumura,Yoshinori Hirose,Ayaha Morita,Madoka Katayama,Makoto Sakuma,Nobuko Kawasaki,Miho Furue,Toshisuke Kawasaki +15 more
TL;DR: R-10G is a novel antibody recognizing hiPS/ES cells, and should be a new molecular probe for disclosing the roles of glycans on these cells.
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Mannan-binding protein and conglutinin in bovine serum.
TL;DR: The present study revealed that bovine plasma contained an MBP besides conglutinin, a lectin specific for mannose and N-acetylglucosamine that was very similar in their chemical and physicochemical properties as well as binding specificity.