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Nobunao Ikewaki
Researcher at Kyushu University of Health and Welfare
Publications - 40
Citations - 314
Nobunao Ikewaki is an academic researcher from Kyushu University of Health and Welfare. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 24 publications receiving 223 citations.
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Journal ArticleDOI
Immunological Actions of Sophy β-Glucan (β-1,3-1,6 Glucan), Currently Available Commercially as a Health Food Supplement
TL;DR: Findings strongly suggest that the Sophy β‐glucan may have unique immune regulatory or enhancing properties that could be exploited by the health food, medical and pharmaceutical industries.
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β-glucans: wide-spectrum immune-balancing food-supplement-based enteric (β-WIFE) vaccine adjuvant approach to COVID-19.
Nobunao Ikewaki,Masaru Iwasaki,Gene Kurosawa,K.S.J. Rao,Johant Lakey-Beitia,Senthilkumar Preethy,Samuel J. K. Abraham +6 more
TL;DR: The complexity of COVID-19 such as the potential mutations of the virus leading to antige... as mentioned in this paper has been identified as a major challenge for conventional vaccines to combat COVID19 through different approaches.
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Evidence of GATA-3-dependent Th2 commitment during the in vivo immune response.
Hidekazu Tamauchi,Masazumi Terashima,Mamoru Ito,Hiroko Maruyama,Nobunao Ikewaki,Matsuhisa Inoue,Xiuhua Gao,Katsuto Hozumi,Sonoko Habu +8 more
TL;DR: Findings provide direct evidence that antigen-stimulated CD4(+) T cells in the immunized mice have already been committed into T(h)2 cells producing IL-5 and IL-13 selectively through enhanced GATA-3 expression in vivo, thereby inducing higher production of antigen-specific antibody for three isotypes other than IgM.
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Unique Properties of a Cytotoxic CD4+CD8+ Intraepithelial T-Cell Line Established from the Mouse Intestinal Epithelium
TL;DR: The established thymoindependent DP andCD8 SP IEL cell lines have unique properties distinct from DP thymocytes and CD8 SP peripheral T cells, which seems to support the notion that DP IEL may undergo a unique maturation process in the gut microenvironment.
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Regulation of CD93 cell surface expression by protein kinase C isoenzymes
TL;DR: Findings indicate that the regulation of CD93 expression on these cells involves the PKC isoenzymes.