N
Nobunao Ikewaki
Researcher at Kyushu University of Health and Welfare
Publications - 40
Citations - 314
Nobunao Ikewaki is an academic researcher from Kyushu University of Health and Welfare. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 24 publications receiving 223 citations.
Papers
More filters
Journal ArticleDOI
Depolymerization of Actin Filament by Cytochalasin E Induces Interleukin‐8 Production and Up‐Regulates CD54 in the HeLa Epithelial Cell Line
TL;DR: It is found that cytochalasin E activates protein kinase C under the depolymerization of actin filament, leading to the induction of interleukin‐8 production and the up‐regulation of CD54 in HeLa cells.
Journal ArticleDOI
Hepatoprotective Effects of Aureobasidium pullulans Derived β 1,3-1,6 Glucans in a Murine Model of Non-alcoholic Steatohepatitis.
Nobunao Ikewaki,Gary A. Levy,Gene Kurosawa,Masaru Iwasaki,Vidyasagar Devaprasad Dedeepiya,Surya Prakash Vaddi,Rajappa Senthilkumar,Senthilkumar Preethy,Samuel J. K. Abraham +8 more
TL;DR: In this paper , the potential of N-163 and AFO-202 beta-glucans alone or in combination as potential preventive and therapeutic agent(s), for NASH was evaluated in a NASH animal model.
Journal ArticleDOI
Potentials to alleviate coagulopathy and enhance microglial function of beta (β)- glucans, making them worth a clinical study for COVID-19's neurological sequalae.
Kadalraja Raghavan,Ramesh Shankar Kandaswamy,Nobunao Ikewaki,Masaru Iwasaki,Samuel J. K. Abraham +4 more
Journal ArticleDOI
Benefits of Gut Microbiota Reconstitution by Beta 1,3-1,6 Glucans in Subjects with Autism Spectrum Disorder and Other Neurodegenerative Diseases.
Kadalraja Raghavan,Vidyasagar Devaprasad Dedeepiya,Naoki Yamamoto,Nobunao Ikewaki,Tohru Sonoda,Masaru Iwasaki,Ramesh Shankar Kandaswamy,Rajappa Senthilkumar,Senthilkumar Preethy,Samuel J. K. Abraham +9 more
TL;DR: AFO-202 beta 1,3-1,6 glucan, in addition to balancing the gut microbiome in children with ASD and its role in effective control of curli-producing Enterobacteriaceae that leads to α-synuclein misfolding and accumulation, may have a prophylactic role in Parkinson's and Alzheimer's diseases as well.
Journal ArticleDOI
A Microfilament Formation Inhibitor, Cytochalasin Strongly Enhances the Low-Affinity Fc ε Receptor II (CD23) Expression on the Human Monocyte-Like Cell Line, U937
Nobunao Ikewaki,Hidekazu Tamauchi,Akira Yamada,Masahito Aoki,Ryuichi Yamamoto,Atsushi Sawada,Hidetoshi Inoko +6 more
TL;DR: The results suggest that a mechanism underlying enhancement of the CD23 expression on the U937 cells cultured with cytochalasin E is mediated through tyrosine phosphorylation and protein synthesis.