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Noema F. Grynberg
Researcher at Universidade Federal Rural do Rio de Janeiro
Publications - 13
Citations - 963
Noema F. Grynberg is an academic researcher from Universidade Federal Rural do Rio de Janeiro. The author has contributed to research in topics: Topoisomerase & Topoisomerase-I Inhibitor. The author has an hindex of 9, co-authored 13 publications receiving 917 citations.
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Journal ArticleDOI
Plantas medicinais: a necessidade de estudos multidisciplinares
Maria Aparecida Medeiros Maciel,Angelo C. Pinto,Valdir F. Veiga,Noema F. Grynberg,Aurea Echevarria +4 more
TL;DR: The chemical composition and pharmacological properties of the very efficient medicinal plant Croton cajucara were investigated according to ethnopharmacological approaches and proved to be both efficient and successful.
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Ethnopharmacology, phytochemistry and pharmacology: a successful combination in the study of Croton cajucara.
Maria Aparecida Medeiros Maciel,Angelo C. Pinto,Alberto C Arruda,Sônia G.S.R. Pamplona,Frederico Argollo Vanderlinde,Antonio José Lapa,Aurea Echevarria,Noema F. Grynberg,Ilce Mara de Syllos Cólus,Rômulo A.F Farias,Angelica M Luna Costa,Vietla Satyanarayana Rao +11 more
TL;DR: The effects of DCTN and CTN on the survival of mice bearing Sarcoma 180 and Ehrlich carcinoma ascitic tumors, on the proliferation of cultured cells and TNFalpha were determined and the terpenoids, DCTn and AAA, and the chloroform extract of 6-month-old plants reduced gastrointestinal transit in mice.
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Anti-tumour activity of two 19-nor-clerodane diterpenes, trans-dehydrocrotonin and trans-crotonin, from Croton cajucara.
Noema F. Grynberg,Aurea Echevarria,Juliana E. Lima,Sônia G.S.R. Pamplona,Angelo C. Pinto,Maria Aparecida Medeiros Maciel +5 more
TL;DR: A significant TNF alpha activity was detected in Ehrlich tumour-bearing mice treated with DCTN suggesting an enhanced immune function.
Journal ArticleDOI
Synthesis, cytotoxicity, and DNA-topoisomerase inhibitory activity of new asymmetric ureas and thioureas.
Andressa Esteves-Souza,Kenia Pissinate,Maria da Graça Nascimento,Noema F. Grynberg,Aurea Echevarria +4 more
TL;DR: The results indicated that the compounds presented important and promising antiproliferative action.
Journal ArticleDOI
Synthesis and in vivo antitumor activity of new heterocyclic derivatives of the 1,3,4-thiadiazolium-2-aminide class
TL;DR: Four new mesoionic compounds derivates of 4-phenyl-5-(4- X-cinnamoyl)-1,3,4-thiadiazolium-2-phenylamine chlorides were synthesized and their antitumor activities against Ehrlich carcinoma and Sarcoma 180 were evaluated.