Noemi Bellassai

TL;DR: This review describes and evaluates the relevance and applicability of surface plasmon resonance (SPR) and localized SPR (LSPR)-based platforms for the detection of different classes of cancer biomarkers in liquid biopsy samples and describes the analytical performances of selected SPR biosensor assays.

TL;DR: In this paper, possibilities offered by innovative biosensing approaches for the detection of circulating DNA in peripheral blood and blood-derived products such as plasma and serum blood are discussed, and different transduction principles are used to detect circulating DNAs and great advantages are derived from the combined use of nanostructured materials.

TL;DR: A mixed-charge polymer prepared by the coupling of a cationic polyelectrolyte and an anionic oligopeptide through a modified "grafting-to" method offers a prominent low-fouling activity in complex media, with rapid and simple procedures for the synthesis and functionalization of the surface compared to conventional non-foul materials.

TL;DR: An ultrasensitive nanoparticle-enhanced plasmonic method for detecting ~1 aM RAS single nucleotide variants (SNVs) in the plasma of CRC patients, proven in plasma from CRC patients and healthy donors, and full discrimination between mutated DNA from patients over wild-type DNA from healthy volunteers was obtained, demonstrating its promising avenue for cancer monitoring based on liquid biopsy.

TL;DR: In this article, a review of surface plasmon resonance (SPR) surface coatings is presented, emphasizing the importance of adopting appropriate antifouling materials for achieving excellent performances in biosensing for food safety and clinical diagnosis.