N
Noemi Reguart
Researcher at The Breast Cancer Research Foundation
Publications - 141
Citations - 13136
Noemi Reguart is an academic researcher from The Breast Cancer Research Foundation. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 39, co-authored 113 publications receiving 11574 citations. Previous affiliations of Noemi Reguart include Gen-Probe Incorporated & University of California, San Francisco.
Papers
More filters
Journal ArticleDOI
Immunotherapy for oncogenic-driven advanced non-small cell lung cancers: Is the time ripe for a change?
TL;DR: There are still several open questions about ICI in oncogenic-driven NSCLC, such as the efficacy and toxicities, which need to be addressed before considering treatment with ICI as a standard approach in this population.
Journal ArticleDOI
Immune checkpoint inhibitors in non-small cell lung cancer (NSCLC): Approaches on special subgroups and unresolved burning questions
TL;DR: Questions remain with regards ICIs activity in patients receiving corticosteroid or antibiotics, the potential use in oncogenic addicted tumours, as well as the safety of retreatment after the onset of immune-related adverse events (ir-AE), the optimal dose schedule or time on treatment for ICIs administration are addressed.
Journal ArticleDOI
Stromal markers of activated tumor associated fibroblasts predict poor survival and are associated with necrosis in non-small cell lung cancer
Jordi Alcaraz,Josep L. Carrasco,Laura Millares,Iuliana-Cristiana Luis,Francisco J. Fernández-Porras,Anabel Martinez-Romero,Natalia Díaz-Valdivia,Julio Sánchez de Cos,Ramon Rami-Porta,Luis Seijo,Josep Ramírez,Maria J. Pajares,Noemi Reguart,Esther Barreiro,Eduard Monsó +14 more
TL;DR: Patients with large histologic coverage of fibrillar collagens and α-SMA + TAFs are identified to be at higher risk of recurrence and death, supporting that they could be considered for adjuvant therapy.
Journal ArticleDOI
Integrin-Specific Mechanoresponses to Compression and Extension Probed by Cylindrical Flat-Ended AFM Tips in Lung Cells
Irene Acerbi,Tomas Luque,Alícia Giménez,Marta Sabariego Puig,Noemi Reguart,Ramon Farré,Daniel Navajas,Jordi Alcaraz +7 more
TL;DR: It is found that cell resistance to compression was globally higher than to extension regardless of the tip coating, and asymmetric resistance to force directionality is an intrinsic property of lung cells, as in most soft tissues.
Journal ArticleDOI
Genome-wide profiling of non-smoking-related lung cancer cells reveals common RB1 rearrangements associated with histopathologic transformation in EGFR-mutant tumors.
Eva Pros,M Saigi,Daniel Alameda,Gema Gomez-Mariano,Beatriz Martinez-Delgado,Juan J. Alburquerque-Bejar,Julian Carretero,Raul Tonda,Anna Esteve-Codina,I. Català,Ramon Palmero,M. Jove,Conxi Lázaro,Ana Patiño-García,Ignacio Gil-Bazo,Ignacio Gil-Bazo,S. Verdura,A Teulé,J Torres-Lanzas,David Sidransky,Noemi Reguart,Ruben Pio,Ruben Pio,O. Juan-Vidal,Ernest Nadal,Enriqueta Felip,Luis M. Montuenga,Luis M. Montuenga,Montserrat Sanchez-Cespedes +28 more
TL;DR: The preferential occurrence of RB1 inactivation, via complex rearrangements, found in EGFR-mutant tumors appears to favor SCLC/LuSCC transformation under growth-inhibition pressures, and demonstrates that a subset of NSK-LuADs arises within cancer-predisposition syndromes.