Noemí Waksman

TL;DR: Bioactivity-guided fractionation of the methanolic root bark extract of Leucophyllum frutescens led to the identification of leubethanol, a new serrulatane-type diterpene with activity against both multi-drug-resistant and drug-sensitive strains of virulent Mycobacterium tuberculosis.

TL;DR: This is the first report of the presence of 5-hydroxy-furanocoumarin in F. vulgare, and the chemical structure of this compound was elucidated by 1H and 13C Nuclear Magnetic Resonance spectroscopy.

TL;DR: In this paper, the assignment of all 1H- and 13C-NMR resonances of the isomers due to restricted C-N amide bond rotation of N-formyl-o-toluidine and N,N'-bis-formed formyl-of-tolidine in DMSO-d6 is reported.

TL;DR: Teuhetenone A was isolated and identified as the main metabolite responsible for the plant’s hypoglycemic activity and suggested that it has potential as an antidiabetic compound, which could be further submitted to preclinical assays.

TL;DR: A series of substituted 2-hydroxysalicylidine benzohydrazides were converted into their phenyl-boron complexes in good yields upon reaction with phenylboronic acid as mentioned in this paper.