N
Norbert Klugbauer
Researcher at Ludwig Maximilian University of Munich
Publications - 22
Citations - 2330
Norbert Klugbauer is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Calcium channel & Protein subunit. The author has an hindex of 19, co-authored 22 publications receiving 2244 citations. Previous affiliations of Norbert Klugbauer include Saarland University.
Papers
More filters
Journal ArticleDOI
Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells.
TL;DR: A member of a new subclass of the voltage‐activated sodium channel genes has been cloned from the human medullary thyroid carcinoma (hMTC) cell line, demonstrating its expression in hMTC cells, in a C‐cell carcinoma, and in thyroid and adrenal gland.
Journal ArticleDOI
Molecular Diversity of the Calcium Channel α2δ Subunit
TL;DR: Coexpression of α2δ-3 with α1C and cardiac β2a or α1E and β3 subunits shifted the voltage dependence of channel activation and inactivation in a hyperpolarizing direction and accelerated the kinetics of current inactivation.
Journal ArticleDOI
Calcium channel alpha(2)delta subunits-structure and Gabapentin binding.
TL;DR: The structure of these two novel α2δ-2 and -3 subunits has been characterized and binding of the antiepileptic drug gabapentin investigated.
Journal ArticleDOI
Alternatively Spliced IS6 Segments of the α1C Gene Determine the Tissue-Specific Dihydropyridine Sensitivity of Cardiac and Vascular Smooth Muscle L-Type Ca2+ Channels
Andrea Welling,Andreas Ludwig,Stephanie Zimmer,Norbert Klugbauer,Veit Flockerzi,Franz Hofmann +5 more
TL;DR: The results suggest that the different dihydropyridine sensitivities of cardiac and vascular L-type Ca2+ channels are caused at least partially by the tissue-specific expression of alternatively spliced IS6 segments of the alpha 1C gene.
Journal ArticleDOI
A family of γ‐like calcium channel subunits
Norbert Klugbauer,Shuiping Dai,Verena Specht,Lubica Lacinová,Elsé Marais,Georg Bohn,Franz Hofmann +6 more
TL;DR: The first account of a family of at least five putative γ subunits that are predominantly expressed in brain is presented, which accelerates the time course of current activation and inactivation of the α1G T‐type calcium channel.