N
Nurith Porat
Researcher at Ben-Gurion University of the Negev
Publications - 102
Citations - 4491
Nurith Porat is an academic researcher from Ben-Gurion University of the Negev. The author has contributed to research in topics: Streptococcus pneumoniae & Serotype. The author has an hindex of 41, co-authored 101 publications receiving 4253 citations. Previous affiliations of Nurith Porat include Rockefeller University & Soroka Medical Center.
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Journal ArticleDOI
Nasopharyngeal carriage of Streptococcus pneumoniae by adults and children in community and family settings.
Gili Regev-Yochay,Gili Regev-Yochay,Meir Raz,Ron Dagan,Nurith Porat,Bracha Shainberg,Erica Pinco,Nathan Keller,Ethan Rubinstein,Ethan Rubinstein +9 more
TL;DR: Young age, day care center attendance, having young siblings, and no antibiotic use during the month before screening were associated with the high carriage rate among children, whereas the only risk factor associated with carriage among adults was the presence of a respiratory infection on the screening day.
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Introduction and proliferation of multidrug-resistant Streptococcus pneumoniae serotype 19A clones that cause acute otitis media in an unvaccinated population.
TL;DR: The introduction and proliferation of multidrug-resistant Sp19A occurred before the introduction of PCV7 and suggests that antibiotic use plays an important role in the community.
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CodY Regulates Thiol Peroxidase Expression as Part of the Pneumococcal Defense Mechanism against H2O2 Stress.
Barak Hajaj,Hasan Yesilkaya,Sulman Shafeeq,Xiangyun Zhi,Rachel Benisty,Shiran Tchalah,Oscar P. Kuipers,Nurith Porat +7 more
TL;DR: It is hypothesized that H2O2 activates a transcription factor which in turn up-regulates tpxD expression, which triggers a conformational change in CodY, resulting in enhanced binding to DNA and a schematic model illustrating the contribution of TpxD and CodY to pneumococcal global transcriptional response to H2 O2 is proposed.
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Comparative Immunogenicity and Efficacy of 13-Valent and 7-Valent Pneumococcal Conjugate Vaccines in Reducing Nasopharyngeal Colonization: A Randomized Double-Blind Trial
Ron Dagan,Scott Patterson,Christine Juergens,David Greenberg,Noga Givon-Lavi,Nurith Porat,Alejandra Gurtman,William C. Gruber,Daniel A. Scott +8 more
TL;DR: PCV13 resulted in lower acquisition and prevalence of NP colonization than PCV7 did for 4 additional PCV13 serotypes, and serotypes 6C and 19F, and it was comparable with PCV 7 for all other common serotypes.
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Acquisition, Carriage, and Transmission of Pneumococci with Decreased Antibiotic Susceptibility in Young Children Attending a Day Care Facility in Southern Israel
Pablo Yagupsky,Nurith Porat,Drora Fraser,Felicia Prajgrod,Marlene Merires,Lesley McGee,Keith P. Klugman,Ron Dagan +7 more
TL;DR: Carriage of organisms with decreased antibiotic susceptibility was associated with young age, female sex, winter season, and exposure to antimicrobial drugs during the previous month.