O
O.Y. So
Publications - 2
Citations - 48
O.Y. So is an academic researcher. The author has contributed to research in topics: Ligand (biochemistry) & Mechanism of action. The author has an hindex of 2, co-authored 2 publications receiving 48 citations.
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Journal ArticleDOI
Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.
David C. Swinney,O.Y. So,Watson Dm,Berry Pw,Webb As,Kertesz Dj,Shelton Ej,Burton Pm,Walker Ka +8 more
TL;DR: RS-21607 is shown to be an effective and selective inhibitor of lanosterol 14 alpha-demethylase, both in vivo and in vitro, and the ligand attached to the imidazole in RS-216 07 is a good non-sterol substitute for DHL.
Journal ArticleDOI
Accumulation of intermediates and isotopically sensitive enolization distinguish between aromatase (cytochrome P450 CYP19) from rat ovary and human placenta.
D.C. Swinney,D.M. Watson,O.Y. So +2 more
TL;DR: It is suggested that for aromatase in both tissues, an enzymatic step exists between the 19-al-androstenedione intermediate and hydrogen abstraction or enolization that has a large commitment to catalysis.