O
Ogun Adebali
Researcher at Sabancı University
Publications - 42
Citations - 1057
Ogun Adebali is an academic researcher from Sabancı University. The author has contributed to research in topics: Nucleotide excision repair & DNA repair. The author has an hindex of 15, co-authored 30 publications receiving 717 citations. Previous affiliations of Ogun Adebali include Oak Ridge National Laboratory & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Cache Domains That are Homologous to, but Different from PAS Domains Comprise the Largest Superfamily of Extracellular Sensors in Prokaryotes
Amit A. Upadhyay,Amit A. Upadhyay,Aaron D. Fleetwood,Aaron D. Fleetwood,Ogun Adebali,Ogun Adebali,Robert D. Finn,Igor B. Zhulin,Igor B. Zhulin +8 more
TL;DR: The newly built computational models enabled identification of Cache domains in tens of thousands of signal transduction proteins including those from important pathogens and model organisms, and it is shown that Cache domains comprise the dominant mode of extracellular sensing in prokaryotes.
Journal ArticleDOI
Dynamic maps of UV damage formation and repair for the human genome.
TL;DR: The combination of the two methods revealed that, whereas UV-induced damage is virtually uniform throughout the genome, repair is affected by chromatin states, transcription, and transcription factor binding, in a manner that depends on the type of DNA damage.
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MiST 3.0: an updated microbial signal transduction database with an emphasis on chemosensory systems.
TL;DR: The updated MiST database provides a comprehensive classification of microbial signal transduction systems, and a novel MiST feature is the integration of unique profile HMMs to link complex chemosensory systems with corresponding chemoreceptors in bacterial and archaeal genomes.
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Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs.
TL;DR: Yimit et al. revert to genome-wide approaches to map and analyze cisplatin damage formation and excision repair with single nucleotide resolution across different mice organs following platinum treatment.
Journal ArticleDOI
Cisplatin-DNA adduct repair of transcribed genes is controlled by two circadian programs in mouse tissues
Yanyan Yang,Ogun Adebali,Gang Wu,Christopher P. Selby,Yi Ying Chiou,Yi Ying Chiou,Naim U. Rashid,Jinchuan Hu,Jinchuan Hu,John B. Hogenesch,Aziz Sancar +10 more
TL;DR: The impact of clock time on excision repair of cisplatin-induced DNA damage at single-nucleotide resolution across the genome in mouse kidney and liver is tested and it is found that genome repair is controlled by two circadian programs.